Neonatal Buzağı İshal Tedavilerine İlave Probiyotik Kullanımının İmmunglobulin M (IgM) ve İmmunglobulin G (IgG) Seviyelerine Etkisi
Yıl 2021,
, 131 - 136, 30.08.2021
Medine Yayan
Yıldıray Basbugan
,
Nazmi Yüksek
,
Ege Çatalkaya
Öz
Yeni doğan buzağı ishalleri önemli ekonomik kayıplara yol açmaktadır. Bu nedenle çalışmamızda buzağı ishallerine ilave olarak probiyotik eklenmesinin İmmunoglobulin M (IgM) ve İmmunoglobulin G (IgG) değerlerine etkisi amaçlandı. Çalışma Van Yüzüncü Yıl Üniversitesi Hayvan Deneyleri Yerel Etik Kurulunun (YÜHADYEK) 28/03/2019 tarih ve 03 sayılı karar yazısı ile onay alınarak yapıldı. Çalışmaya ishal şikâyeti ile olan 6 adet buzağıya rutin tedaviye ilaveten Probiyotik ilave edildi Probiyotik grubu (1. Grup) ve 6 buzağı ya da sadece rutin tedavi uygulandı. (2. Grup) Rutin tedavi grubu. Çalışmaya toplam 12 ishalli buzağıda dahil edildi. IgM değerlerinde 1. Grupta Tedavi Sonrasında (TS), Tedavi Öncesine (TÖ) göre istatistikî (p<0,05) olarak artış olduğu, TS 2. Gruba göre de istatistikî artış görüldü. İmmunoglobulin G (IgG) değerlerinde ise iki gruptada TÖ ve TS fark belirlenemedi. Sonuç olarak yeni doğan buzağı ishallerinde rutin tedaviye ek olarak probiyotik eklenmesinin yayarlı olabileceği, İleride konuyla ilgili daha detaylı çalışmaların yapılması gerektiği kanısına varıldı.
Destekleyen Kurum
TÜBİTAK
Proje Numarası
1919B011900177
Teşekkür
TÜBİTAK 2209-A Üniversite Öğrencileri Araştırma Projeleri Destekleme Programında, 1919B011900177 Numaralı projemize verdikleri destekten dolayı teşekkür ederiz.
Kaynakça
- Akşit, F., Akgün, Y., Kiraz, N., 1996. Mikrobiyoloji. Anadolu Üniversitesi Yayınları, Eskişehir.
- Al Saiady MY. Effect of Probiotic Bacteria on Immunglobulın G Concentration and Other Blood Components of Newborn Calves. J Anim Vet Adv. 2010; 9 (3):604-609.
Altuğ, N; Özdemir, R; Cantekin, Z. Ruminantlarda Koruyucu Hekimlik: I. Aşı Uygulamaları. Erciyes Üniv Vet Fak Derg. 2013, 10(1): 33-44.
- Argenzio RA. Pathophysiology of neonatal calf diarrhea. Vet Clin North Am Food Anim Pract 1985;1(3):461.
- Basoglu A, Sen İ, Sevinç M, Simsek A. Serum concentrations of tumor necrosis factor-alpha in neonatal calves with presumed septicemia. J Vet Intern Med., 2004;18(2):238-41
- Berlot G, Bacer B, Piva M, Lucangelo U, Viviani M. Immunoglobulins in sepsis. Advances In Sepsis, Advances in sepsis, 2007; 6 (2), 41-46.
- Blıss, J M.; Wynn, J L. The Neonatal Immune System: A Unique Host-Microbial Interface. Frontiers in pediatrics, 2017, 5: 274.
- Boersema SJ, Silva JC, Mee J, Noordhuzien J. Infectious calf diarrhoea and septicemia in Farm health and productivity management of dairy young stock. ISBN: 978-90-8686-129-3 1st ed. Netherland Wageningen Academic Publishers, 2010.
- Castagliuolo LM, Riegler MF, Valenick I, La Mont JT, Pathoulakis C. Saccharomyces boulardii; protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect. Immun., 1999; 67, 302-307.
- Çakıroğlu D, Meral Y, Pekmezci D, Onuk EE, Gökalp G. Yeni doğan buzağılarda çeşitli hematolojik ve biyokimyasal parametreler ile kolostral immun globulinler arasındaki ilişkinin belirlenmesi. Fırat Üniv. Sağlık Bil. Vet. Derg., 2010; 24 (1), 43-46.
- Diker KS. İmmunoloji. Medisan Yayınları; Ankara. 2005.
- Eales LJ. Immunology for Life Scientists, Second Edition, chapter one. Chichester, England. 2003
- Erdoğan HM, Ünver, A, Çitil M, Güneş V, Arslan MÖ, Tuzcu M, Gökçe Hİ. Dairy farming in Kars district, Turkey: III. Neonatal calf health. Turk. J. Vet. Anim. Sci.2009; 33(3): 185-192.
- Ghosh S and Mehla RK. Influence of Dietary Supplementation of Prebiotics (Mannanoligosaccharide) on the Performance of Crossbred Calves. Trop Anim Health Prod. 2012; 44:617-622.
- Guerin-Danan C, Chabenet C, Pedone C, Po-pot F. Milk fermented with yogurt cultures and lactobacillus casei compared with yogurt and gelled milk influence on intestinal microflora in healthy infants. J. Clin. Nutr., 1998; 67, 111-117
- Heczko PB, Strus M, Kochan P. Critical evaluation of probiotic activity and lactic acid bacteria and their effects. J. Physiol. Pharm., 2006; 57 (9): 5-12.
- Heinrichs AJ, Jones CM, Heinrichs BS. Effects of Mannan Oligosaccharide or Antibiotics in Neonatal Diets on Health and Growth of Dairy Calves. J Dairy Sci, 2003; 86(12): 4064-4069.
- Hennequin C and Kaufmann-Lacroix C. Possible role of catheters in Saccharomyces boulardi fungemia. Eur. J. Clin. Microbiol. Infect. Dis., 2002; 19, 16-20.
- Hou S, Riley CB, Mitchell C, Shaw RA, Bryanton J , Bigsby K, McClure JT. Exploration of attenuated total reflectance mid-infrared spectroscopy and multivariate calibration to measure immunoglobulin G in human sera. Talanta, 2015; 142, 110–119.
- Jenkins DJA, Kendall CWC, Vuksan V. Inulin, Oligofructose and Intestinal Function. J Nutr., 1999; 129(7): 1431-1433.
- Kognoff MF. Immunology of the intestinal tract. Gastroenterology, 1993; 105, 1275-1280.
- Kreymann KG, de Heer G, Nierhaus A, Kluge S. Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock. Critical Care Medicine, 2007; 35 (12), 2677-2685.
- Maragkoudakis PA, Mountzouris KC, Rosu C, Zoumpopoulou G, Papadimitriou K, Dalaka E, et al. Feed supplementation of Lactobacillus Plantarum PCA 236 modulates gut microbiota and milk fatty acid composition in dairy goats a preliminary study. Int J Food Microbial 2010; 141:109-16.
- Mathieu F, Sudirman I, Rekhif N. Mesenterocin 52, a bacteriocin produced by Leuconostoc Mesenteroides Ssp. Mesenteroides Fr 52. J. Appl. Bacteriol., 1993; 74, 372- 379.
- Norby-Teglund, A., Haque, K.N., Hammarström, L. Intravenous polyclonal IgM-enriched immunoglobulin therapy in sepsis: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis. JIM, 2006; 260 (6), 509-516.
- Oesser S, Schulze C, Seifert J. Protective capacity of a IgM/IgA-enriched polyclonal immunoglobulin-G preparation in endotoxemia. Research in Experimental Medicine, 1999; 198 (6), 325-339.
- Pleass RJ, Moore SC, Stevenson L, Hviid L (2015). Immunoglobulin M: Restrainer of Inflammation and Mediator of Immune Evasion by Plasmodium falciparum Malaria. Trepar, 1431 1–12.
- Quıgley JD, Kost CJ and Wolfe, TA. Effects of Spray-Dried Animal Plasma in Milk Replacers or Additives Containing Serum and Oligosaccharides on Growth and Health of Calves. J. Dairy Sci., 2002; 85:413-421.
- Quigley JD, Drewry JJ, Murray LM, Ivey SJ. Body weight gain, feed efficiency and fecal scores of dairy calves in response to galactosyl-lactose or antibiotics in milk replacers. J Dairy Sci, 1997; 80(8): 1751-1754.
- Reid G, Jass J, Sebulsky MT, Mc Cormick JK. Potential uses of probiotics Reid in clinical practice. Clinic Microbiol. Rev., 2003; 16, 658-672.
- Roodposhti PM, Dabiri N. Effects of probiotic and prebiotic on average Daily gain, fecal shedding of Escherichia coli and immune system status in newborn female calves. Asian-Australasian journal of animal sciences. 2012; 25:1255.
- Roosa TB, Tabeleaoa VC, Dummerb LA, Schweglera E, Goularta MA, Mouraa SV, et al. Effect of bacillus cereus var. Toyoi and Saccharomyces boulardii on the immune response of sheep to vaccines. Foof and Agricultural Immunology 2020; 21(2):113-8
- Schedel I ve Dreichhausen U. The therapy of gram-negative septicotoxic diseases with pentaglobin, an immunoglobulin with an elevated IgM content (a prospective, randomized clinical study). Anesteziologiia i Reanimatologiia, 1995; 199, 4-9.
- Şahal M, Terzi OS, Ceylan E, Kara E. Buzağı İshalleri ve Korunma Yöntemleri. Lalahan Hay. Araşt. Enst. DergDerleme / Review. 2018; 58, 41-49.
- Şentürk E., Esen F. Sepsiste immunoglobülin tedavisi ile kompleman inhibisyonu ve nöroproteksiyon. TARD, 2012; 40 (4), 184-192.
- Tokgöz BS, Özdemir R, Turgut N, Mirioğlu M, İnce H, Mahanoğlu B, Yoldaş A, Tuzcu N. Adana Bölgesinde Görülen Neonatal Buzağı Enfeksiyonlarının Morbidite ve Mortaliteleri ve Risk Faktörlerinin Belirlenmesi. AVKAE Derg. 2013; 3(1): 7-14.
- Tuomola EM, Ouwehand AC, Salminen SJ. The effect of probiotic bacteria on the adhesion of pathogensto human intestinal mucus. FEMS Immunol. Medical Microbiol., 1999; 26, 137-142.
- Zhang S, Yang H, Ji X, Wang Q (2016). Binding analysis of carbon nanoparticles to human immunoglobulin G: Elucidation of the cytotoxicity of CNPs and perturbation of immunoglobulin conformations, Spectrochimica Acta Part A. Mol Biomol Spectrosc, 154, 33–41.
The Effect of Probiotic use on İmmunglobulin M (Ig M) and İmmunglobulin G (Ig G) Levels with Routine Treatment in Neonatal Calf Diarrhea
Yıl 2021,
, 131 - 136, 30.08.2021
Medine Yayan
Yıldıray Basbugan
,
Nazmi Yüksek
,
Ege Çatalkaya
Proje Numarası
1919B011900177
Kaynakça
- Akşit, F., Akgün, Y., Kiraz, N., 1996. Mikrobiyoloji. Anadolu Üniversitesi Yayınları, Eskişehir.
- Al Saiady MY. Effect of Probiotic Bacteria on Immunglobulın G Concentration and Other Blood Components of Newborn Calves. J Anim Vet Adv. 2010; 9 (3):604-609.
Altuğ, N; Özdemir, R; Cantekin, Z. Ruminantlarda Koruyucu Hekimlik: I. Aşı Uygulamaları. Erciyes Üniv Vet Fak Derg. 2013, 10(1): 33-44.
- Argenzio RA. Pathophysiology of neonatal calf diarrhea. Vet Clin North Am Food Anim Pract 1985;1(3):461.
- Basoglu A, Sen İ, Sevinç M, Simsek A. Serum concentrations of tumor necrosis factor-alpha in neonatal calves with presumed septicemia. J Vet Intern Med., 2004;18(2):238-41
- Berlot G, Bacer B, Piva M, Lucangelo U, Viviani M. Immunoglobulins in sepsis. Advances In Sepsis, Advances in sepsis, 2007; 6 (2), 41-46.
- Blıss, J M.; Wynn, J L. The Neonatal Immune System: A Unique Host-Microbial Interface. Frontiers in pediatrics, 2017, 5: 274.
- Boersema SJ, Silva JC, Mee J, Noordhuzien J. Infectious calf diarrhoea and septicemia in Farm health and productivity management of dairy young stock. ISBN: 978-90-8686-129-3 1st ed. Netherland Wageningen Academic Publishers, 2010.
- Castagliuolo LM, Riegler MF, Valenick I, La Mont JT, Pathoulakis C. Saccharomyces boulardii; protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect. Immun., 1999; 67, 302-307.
- Çakıroğlu D, Meral Y, Pekmezci D, Onuk EE, Gökalp G. Yeni doğan buzağılarda çeşitli hematolojik ve biyokimyasal parametreler ile kolostral immun globulinler arasındaki ilişkinin belirlenmesi. Fırat Üniv. Sağlık Bil. Vet. Derg., 2010; 24 (1), 43-46.
- Diker KS. İmmunoloji. Medisan Yayınları; Ankara. 2005.
- Eales LJ. Immunology for Life Scientists, Second Edition, chapter one. Chichester, England. 2003
- Erdoğan HM, Ünver, A, Çitil M, Güneş V, Arslan MÖ, Tuzcu M, Gökçe Hİ. Dairy farming in Kars district, Turkey: III. Neonatal calf health. Turk. J. Vet. Anim. Sci.2009; 33(3): 185-192.
- Ghosh S and Mehla RK. Influence of Dietary Supplementation of Prebiotics (Mannanoligosaccharide) on the Performance of Crossbred Calves. Trop Anim Health Prod. 2012; 44:617-622.
- Guerin-Danan C, Chabenet C, Pedone C, Po-pot F. Milk fermented with yogurt cultures and lactobacillus casei compared with yogurt and gelled milk influence on intestinal microflora in healthy infants. J. Clin. Nutr., 1998; 67, 111-117
- Heczko PB, Strus M, Kochan P. Critical evaluation of probiotic activity and lactic acid bacteria and their effects. J. Physiol. Pharm., 2006; 57 (9): 5-12.
- Heinrichs AJ, Jones CM, Heinrichs BS. Effects of Mannan Oligosaccharide or Antibiotics in Neonatal Diets on Health and Growth of Dairy Calves. J Dairy Sci, 2003; 86(12): 4064-4069.
- Hennequin C and Kaufmann-Lacroix C. Possible role of catheters in Saccharomyces boulardi fungemia. Eur. J. Clin. Microbiol. Infect. Dis., 2002; 19, 16-20.
- Hou S, Riley CB, Mitchell C, Shaw RA, Bryanton J , Bigsby K, McClure JT. Exploration of attenuated total reflectance mid-infrared spectroscopy and multivariate calibration to measure immunoglobulin G in human sera. Talanta, 2015; 142, 110–119.
- Jenkins DJA, Kendall CWC, Vuksan V. Inulin, Oligofructose and Intestinal Function. J Nutr., 1999; 129(7): 1431-1433.
- Kognoff MF. Immunology of the intestinal tract. Gastroenterology, 1993; 105, 1275-1280.
- Kreymann KG, de Heer G, Nierhaus A, Kluge S. Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock. Critical Care Medicine, 2007; 35 (12), 2677-2685.
- Maragkoudakis PA, Mountzouris KC, Rosu C, Zoumpopoulou G, Papadimitriou K, Dalaka E, et al. Feed supplementation of Lactobacillus Plantarum PCA 236 modulates gut microbiota and milk fatty acid composition in dairy goats a preliminary study. Int J Food Microbial 2010; 141:109-16.
- Mathieu F, Sudirman I, Rekhif N. Mesenterocin 52, a bacteriocin produced by Leuconostoc Mesenteroides Ssp. Mesenteroides Fr 52. J. Appl. Bacteriol., 1993; 74, 372- 379.
- Norby-Teglund, A., Haque, K.N., Hammarström, L. Intravenous polyclonal IgM-enriched immunoglobulin therapy in sepsis: a review of clinical efficacy in relation to microbiological aetiology and severity of sepsis. JIM, 2006; 260 (6), 509-516.
- Oesser S, Schulze C, Seifert J. Protective capacity of a IgM/IgA-enriched polyclonal immunoglobulin-G preparation in endotoxemia. Research in Experimental Medicine, 1999; 198 (6), 325-339.
- Pleass RJ, Moore SC, Stevenson L, Hviid L (2015). Immunoglobulin M: Restrainer of Inflammation and Mediator of Immune Evasion by Plasmodium falciparum Malaria. Trepar, 1431 1–12.
- Quıgley JD, Kost CJ and Wolfe, TA. Effects of Spray-Dried Animal Plasma in Milk Replacers or Additives Containing Serum and Oligosaccharides on Growth and Health of Calves. J. Dairy Sci., 2002; 85:413-421.
- Quigley JD, Drewry JJ, Murray LM, Ivey SJ. Body weight gain, feed efficiency and fecal scores of dairy calves in response to galactosyl-lactose or antibiotics in milk replacers. J Dairy Sci, 1997; 80(8): 1751-1754.
- Reid G, Jass J, Sebulsky MT, Mc Cormick JK. Potential uses of probiotics Reid in clinical practice. Clinic Microbiol. Rev., 2003; 16, 658-672.
- Roodposhti PM, Dabiri N. Effects of probiotic and prebiotic on average Daily gain, fecal shedding of Escherichia coli and immune system status in newborn female calves. Asian-Australasian journal of animal sciences. 2012; 25:1255.
- Roosa TB, Tabeleaoa VC, Dummerb LA, Schweglera E, Goularta MA, Mouraa SV, et al. Effect of bacillus cereus var. Toyoi and Saccharomyces boulardii on the immune response of sheep to vaccines. Foof and Agricultural Immunology 2020; 21(2):113-8
- Schedel I ve Dreichhausen U. The therapy of gram-negative septicotoxic diseases with pentaglobin, an immunoglobulin with an elevated IgM content (a prospective, randomized clinical study). Anesteziologiia i Reanimatologiia, 1995; 199, 4-9.
- Şahal M, Terzi OS, Ceylan E, Kara E. Buzağı İshalleri ve Korunma Yöntemleri. Lalahan Hay. Araşt. Enst. DergDerleme / Review. 2018; 58, 41-49.
- Şentürk E., Esen F. Sepsiste immunoglobülin tedavisi ile kompleman inhibisyonu ve nöroproteksiyon. TARD, 2012; 40 (4), 184-192.
- Tokgöz BS, Özdemir R, Turgut N, Mirioğlu M, İnce H, Mahanoğlu B, Yoldaş A, Tuzcu N. Adana Bölgesinde Görülen Neonatal Buzağı Enfeksiyonlarının Morbidite ve Mortaliteleri ve Risk Faktörlerinin Belirlenmesi. AVKAE Derg. 2013; 3(1): 7-14.
- Tuomola EM, Ouwehand AC, Salminen SJ. The effect of probiotic bacteria on the adhesion of pathogensto human intestinal mucus. FEMS Immunol. Medical Microbiol., 1999; 26, 137-142.
- Zhang S, Yang H, Ji X, Wang Q (2016). Binding analysis of carbon nanoparticles to human immunoglobulin G: Elucidation of the cytotoxicity of CNPs and perturbation of immunoglobulin conformations, Spectrochimica Acta Part A. Mol Biomol Spectrosc, 154, 33–41.