Evaluation of the effect of various therapeutic agents on osseointegration of dental implants: Complications in a rabbit tibia model

Yıl 2023, Cilt: 16 Sayı: 2, 183 - 188, 30.08.2023

Ahmet Cemil Talmaç , Bilal Ege , Nazlı Zeynep Alpaslan , Metin Çalışır

https://doi.org/10.52976/vansaglik.1315756

Öz

Objective: The aim of our study is to evaluate the complications that occurred on rabbit tibia bones after implant placement.
Material and Method: In our study, 10 adult male white healthy New Zealand rabbits (average weight: 3,000 to 3,500 g) were used. Different numbers of dental implants were placed in the experimental animals. Complications in rabbit tibias were observed and radiological results were reported.
Results: Of the 10 rabbits included in the postoperative study, one (10%) died immediately after the operation, eight (80%) within the first 24 hours, and the last one (10%) died within the next 48 hours of the operation.
Conclusion: Based on the complications experienced during this study and the data we obtained, we conclude that the rabbit tibia is not suitable for such studies. More comprehensive and multi-center studies are needed to draw more firm conclusions on this subject.

Anahtar Kelimeler

Dental İmplant, Experimental animals, Rabbit, Complications

Destekleyen Kurum

Van Yuzuncu Yıl University Scientific Research Project

Proje Numarası

TSA-2019-8658

Çeşitli terapötik ajanların dental implantların osseointegrasyonu üzerine olan etkisinin incelenmesi: Tavşan tibia modelinde görülen komplikasyonlar

Öz

Amaç: Çalışmamızın amacı, yerleştirilen implantlar sonrası tavşan tibia kemikleri üzerinde meydana gelen komplikasyonları değerlendirmektir.
Materyal ve Metot: Çalışmamızda sağlıklı (ortalama ağırlığı 3000–3500 g), 10 adet yetişkin erkek, beyaz Yeni Zelanda tavşanı kullanılmıştır. Deney hayvanlarına farklı sayılarda (1-3) dental implant yerleştirilmiştir. Tavşan tibialarındaki komplikasyonlar gözlenmiştir ve radyolojik sonuçları bildirilmiştir.
Bulgular: Operasyon sonrası çalışmaya dahil edilen 10 tavşandan biri (%10) operasyondan hemen sonra, sekizi (%80) operasyon sonrası ilk 24 saat içerisinde ve kalan biri (%10) sonraki 48 saat içerisinde kaybedilmiştir.
Sonuç: Çalışmamız süresince yaşanan komplikasyonlar ve elde etiğimiz verilere göre bu tür çalışmalar için tavşan tibiasının uygun olmadığı sonucuna varılmıştır. Kesin sonuçlar için daha kapsamlı ve çok merkezli çalışmalara gereksinim vardır.

Anahtar Kelimeler

Dental implant, Deney hayvanları, Tavşan, Komplikasyon

Proje Numarası

TSA-2019-8658

Kaynakça

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