The Important Role of Antioxidants in The Relationship Between Oxidative Stress And Colorectal Cancer

Yıl 2024, Cilt: 17 Sayı: 2, 119 - 124, 30.08.2024

Zeynep Bozkoyun Dusak , Yusuf Ziya Yaşar , Ayşe Şaprak

https://doi.org/10.52976/vansaglik.1443021

Öz

The body has a complex enzymatic and non-enzymatic antioxidant defense system. Antioxidant mechanisms develop a defense system against free radicals that have harmful effects on body tissues. The accumulation of free radicals in the cell causes oxidative stress and cellular damage. It is known that the increase in cell reactive oxygen species plays a role in the pathogenesis of many diseases such as colon cancer, neurodegenerative, cardiovascular, diabetes and kidney diseases. The aim of our study is to reveal the effect of oxidative stress on colorectal cancer and the opposing effects of antioxidants (such as SOD, CAT and GPx).determined that the factors in the autumn season differ proportionally according to the summer and winter months.

Anahtar Kelimeler

Antioxidants, Colon Cancer, Oxidative Stress, Free Radicals

Oksidatif Stres ve Kolorektal Kanser İlişkisinde Antioksidanların Önemli Rolü

Öz

Kolorektal kanser günümüzde en sık görülen kanserlerden biri olup, yaşam kalitesini düşüren, iş kaybına yol açan önemli bir sağlık sorunudur. Birçok kanser türünde olduğu gibi oksidatif stres ve inflamasyonun kolorektal kanserin oluşumunu ve ilerlemesini arttırdığı düşünülmektedir. Çalışmamızın amacı oksidatif stresin kolorektal kanser üzerindeki etkisini ve antioksidanların karşıt etkilerini ortaya koymaktır.

Anahtar Kelimeler

Antioksidanlar, Kolon Kanseri, Oksidatif Stres, Serbest Radikaller

Kaynakça

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