CHRYSIN: POTENTIAL PHARMACOLOGICAL and TOXICOLOGICAL EFFECTS

Yıl 2021, Cilt: 12 Sayı: 3, 151 - 160, 29.12.2021

Esra Zeybek Asım Kart

https://doi.org/10.38137/vftd.995966

Cited By: 1

Öz

Recently, the use of pharmacotherapeutic agents of plant origin is increasing as an alternative to synthetic chemical drugs. Although quite a lot of plant-based bioactive ingredients have been reported, the bioactive molecule chyrisin, which is found in some products such as blue passionflower, honey and propolis, has become a remarkable phytochemical in recent years. Chrysin is an important flavonoid that stands out with its strong antioxidant, anticarcinogenic and anxiolytic properties as well as having many different pharmacological effects. In this review, it is aimed to give information about the physicochemical, pharmacokinetic, pharmacodynamic properties of chrysin and its protective and beneficial properties in various diseases.

Anahtar Kelimeler

Chrysin, flavonoid, passiflora, Honey, Propolis

KRİSİN: POTANSİYEL FARMAKOLOJİK ve TOKSİKOLOJİK ETKİLERİ

Öz

Günümüzde sentetik kimyasal ilaçlara alternatif olarak bitki kökenli farmakoterapötik ajanların kullanımı artmaktadır. Oldukça fazla bitki bazlı biyoaktif bileşen bildirilmiş olsa da mavi çarkıfelek, bal ve propolis gibi bazı ürünlerde bulunan biyoaktif molekül krisin, son yıllarda dikkat çekici bir fitokimyasal haline gelmiştir. Krisin, birçok farklı farmakolojik etkiye sahip olmasının yanı sıra güçlü antioksidan, antikanserojenik ve anksiyolitik özellikleri ile öne çıkan önemli bir flavonoiddir. Bu derlemede krisinin fizikokimyasal, farmakokinetik, farmakodinamik özellikleri ve çeşitli hastalıklarda koruyucu ve faydalı özellikleri hakkında bilgi verilmesi amaçlanmıştır.

Anahtar Kelimeler

Chrysin, flavonoid, Bal, Propolis

Kaynakça

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