Araştırma Makalesi
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Altın otu (Helichrysum italicum) esansiyel yağının mikrokapsüle edilmesi ve karakterizasyonu

Yıl 2022, Cilt: 59 Sayı: 4, 669 - 684, 31.12.2022
https://doi.org/10.20289/zfdergi.1093914

Öz

Amaç: Bu çalışmanın amacı altın otu esansiyel yağı ve argan yağı karışımının yanıt yüzey metodolojisi (YYM) koşullarında mikrokapsüle edilmesi ve uygun krem formülasyonundaki antioksidan aktivitesinin belirlenmesidir.
Materyal ve Yöntem: YYM deney tasarımı kullanılarak, kompleks koaservasyon yöntemi ile mikrokapsül üretilmiştir.
Araştırma Bulguları: Altın otu esansiyel yağı ve argan yağı karışımlı, jelatin/arap zamkı duvarlı mikrokapsüller üretilmiş ve karakterize edilmiştir. Oluşturulan deney tasarımına verilerimiz işlenerek ANOVA sonuçları elde edilmiştir. Mikrokapsül içeren kremin antioksidan kapasitesi yüksek bulunmuştur.
Sonuç: YYM ile üç farklı parametrede, kompleks koaservasyon yöntemiyle mikrokapsül üretilip, karakterize edilmiştir. Mikrokapsüllerin morfolojik görüntüleri için SEM (taramalı elektron mikroskobu) ve optik mikroskoptan yararlanılmış olup, yapıyı aydınlatmak için GC-MS (gaz kromatografisi-kütle spektroskopisi) ve FT-IR (Fourier dönüşümlü kızılötesi spektroskopisi) kullanılmıştır. Mikrokapsüller kreme eklenip, kremin antioksidan kapasitesi CUPRAC metoduyla yorumlanmıştır. Tüm veriler değerlendirildiğinde altın otu ve argan yağı karışımı kompleks koaservasyon yöntemi kullanılarak başarılı bir şekilde mikrokapsüle edilmiştir. Mikrokapsül içeren kozmetik kremin etkin bir şekilde antioksidan kapasiteye sahip olduğu görülmüştür.

Destekleyen Kurum

SDÜ-Bilimsel Araştırma Projeleri Koordinasyon Birimi

Proje Numarası

FYL-2022-8645

Teşekkür

Bu çalışma, Süleyman Demirel Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi tarafından ‘FYL-2022-8645 ’kodlu proje ile desteklenmiştir.

Kaynakça

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  • Apak, R., K. Güçlü, M. Özyürek & S.E. Karademir, 2004. Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal of Agricultural and Food Chemistry, 52 (26): 7970-7981. https: //doi.org/10.1021/jf048741x
  • Arenas-Jal, M., J.M. Suñé-Negre & E. García-Montoya, 2020. An overview of microencapsulation in the food industry: opportunities, challenges and innovations. European Food Research and Technology, 246 (7): 1371-1382. https: //doi.org/10.1007/s00217-020-03496-x
  • Bayram, O., E. Köksal & F. Göde, 2020. Yanıt yüzey metodolojisi şartlarında karabaş otu yağının kompleks koaservasyon yöntemi ile enkapsülasyonu. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 24 (2): 508-515. https: //doi.org/10.19113/sdufenbed.687943
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  • Erdoğan, Ü. & E.H. Gökçe, 2021. Fig seed oil‐loaded nanostructured lipid carriers: Evaluation of the protective effects against oxidation. Journal of Food Processing & Preservation, 45 (10): e15835. https: //doi.org/10.1111/jfpp.15835
  • Erdoğan, Ü., 2022. Antioxidant activities and chemical composition of essential oil of rhizomes of Zingiber officinale (ginger) and Curcuma longa L.(turmeric). International Journal of Secondary Metabolite, 9 (2): 137-148. https://doi.org/10.21448/ijsm.993906
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Microencapsulation and characterization of immortelle (Helichrysum italicum) essential oil

Yıl 2022, Cilt: 59 Sayı: 4, 669 - 684, 31.12.2022
https://doi.org/10.20289/zfdergi.1093914

Öz

Objective: The objective of this study was to microencapsulation of a mixture of immortelle essential oil and argan oil under response surface methodology (RSM) conditions and determination of antioxidant activity in the appropriate cream formulation.
Material and Methods: Microcapsule was produced by complex coacervation method using RSM experimental design.
Results: Microcapsules with a mixture of immortelle essential oil and argan oil, with gelatin/gum arabic walls were produced and characterized. ANOVA results were obtained by processing the data obtained in this study. The antioxidant capacity of the cream containing microcapsules was found to be high.
Conclusion: Microcapsules were produced and characterized by complex coacervation method in three different parameters with RSM. SEM (scanning electron microscope) and optical microscope were used for morphological images of microcapsules, and GC-MS (gas chromatography-mass spectroscopy) and FT-IR (Fourier transform infrared spectroscopy) were used to elucidate the structure. Microcapsules were added to the cream and the antioxidant capacity of the cream was interpreted by the CUPRAC method. When all data were evaluated, a mixture of immortelle and argan oil was successfully microencapsulated using the complex coacervation method. It was found that the cosmetic cream containing microcapsules has an effective antioxidant capacity.

Proje Numarası

FYL-2022-8645

Kaynakça

  • Alaoui, K., 2009. L’arganier ou la richesse d’un patrimoine. Phytothérapie, 7 (3): 150-156. https: //doi.org/10.1007/s10298-009-0382-y
  • Andjić, M., B. Božin, N. Draginić, A. Kočović, J.N. Jeremić, M. Tomović & J. V. Bradić, 2021. Formulation and evaluation of Helichrysum italicum essential oil-based topical formulations for wound healing in diabetic rats. Pharmaceuticals, 14 (8): 813. https://doi.org/10.3390/ph14080813
  • Apak, R., K. Güçlü, M. Özyürek & S.E. Karademir, 2004. Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal of Agricultural and Food Chemistry, 52 (26): 7970-7981. https: //doi.org/10.1021/jf048741x
  • Arenas-Jal, M., J.M. Suñé-Negre & E. García-Montoya, 2020. An overview of microencapsulation in the food industry: opportunities, challenges and innovations. European Food Research and Technology, 246 (7): 1371-1382. https: //doi.org/10.1007/s00217-020-03496-x
  • Bayram, O., E. Köksal & F. Göde, 2020. Yanıt yüzey metodolojisi şartlarında karabaş otu yağının kompleks koaservasyon yöntemi ile enkapsülasyonu. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 24 (2): 508-515. https: //doi.org/10.19113/sdufenbed.687943
  • Boukhobza, M. & N. Pichon-Prun, 1988. L’arganier ressource économique et médicinale pour le Maroc. Phytothérapie, 27: 21-26.
  • Charrouf, Z. & D. Guillaume, 2014. Argan oil, the 35‐years‐of‐research product. European Journal of Lipid Science and Technology, 116 (10): 1316-1321. https: //doi.org/10.1002/ejlt.201400261
  • Charrouf, Z. & D. Guillaume, 2018. The argan oil project: going from utopia to reality in 20 years. OCL, 25 (2): D209. https: //doi.org/10.1051/ocl/2018006
  • Charrouf, Z., D. Guillaume & A. Driouich, 2002. The argan tree, an asset for Morocco. Biofutur, 220: 54-57.
  • Costa, P., J.M. Loureiro, M.A. Teixeira & A.E. Rodrigues, 2015. Extraction of aromatic volatiles by hydrodistillation and supercritical fluid extraction with CO2 from Helichrysum italicum subsp. picardii growing in Portugal. Industrial Crops and Products, 77: 680-683. https: //doi.org/10.1016/j.indcrop.2015.09.042
  • Erdoğan, Ü. & E.H. Gökçe, 2021. Fig seed oil‐loaded nanostructured lipid carriers: Evaluation of the protective effects against oxidation. Journal of Food Processing & Preservation, 45 (10): e15835. https: //doi.org/10.1111/jfpp.15835
  • Erdoğan, Ü., 2022. Antioxidant activities and chemical composition of essential oil of rhizomes of Zingiber officinale (ginger) and Curcuma longa L.(turmeric). International Journal of Secondary Metabolite, 9 (2): 137-148. https://doi.org/10.21448/ijsm.993906
  • Ferraz, C.A., A.C.A Sousa, D. Caramelo, F. Delgado, A.P. de Oliveira & M.R. Pastorinho, 2022. Chemical profile and eco-safety evaluation of essential oils and hydrolates from cistus ladanifer, Helichrysum italicum, Ocimum basilicum and Thymbra capitata. Industrial Crops & Products, 175: 114232. https: //doi.org/10.1016/j.indcrop.2021.114232
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  • Guillaume, D. & Z. Charrouf, 2011. Argan oil and other argan products: Use in dermocosmetology. European Journal of Lipid Science and Technology, 113 (4): 403-408. https: //doi.org/10.1002/ejlt.201000417
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  • Han, X., C. Beaumont & N. Stevens, 2017. Chemical composition analysis and in vitro biological activities of ten essential oils in human skin cells. Biochimie Open, 5: 1-7. https: //doi.org/10.1016/j.biopen.2017.04.001
  • Harhaun, R., O. Kunik, D. Saribekova & G. Lazzara, 2020. Biologically active properties of plant extracts in cosmetic emulsions. Microchemical Journal, 154: 104543. https: //doi.org/10.1016/j.microc.2019.104543
  • Hu, L., J. Zhang, Q. Hu, N. Gao, S. Wang, Y. Sun & X. Yang, 2016. Microencapsulation of brucea javanica oil: characterization, stability and optimization of spray drying conditions. Journal of Drug Delivery Science and Technology, 36: 46-54. https: //doi.org/10.1016/j.jddst.2016.09.008
  • Kabouss, A.E., Z. Charrouf, M. Faid, F.X. Garneau & G. Collin, 2002. Chemical composition and antimicrobial activity of the leaf essential oil of Argania spinosa L. skeels. Journal of Essential Oil Research, 14 (2): 147-149. https: //doi.org/10.1080/10412905.2002.9699801
  • Kaushik, P., K. Dowling, C.J. Barrow & B. Adhikari, 2015. Microencapsulation of omega-3 fatty acids: A review of microencapsulation and characterization methods. Journal of Functional Foods, 19: 868-881. https: //doi.org/10.1016/j.jff.2014.06.029
  • Khallouki, F., M. Eddouks, A. Mourad, A. Breuer & R.W. Owen, 2017. Ethnobotanic, ethnopharmacologic aspects and new phytochemical insights into Moroccan argan fruits. International Journal of Molecular Sciences, 18 (11): 2277. https: //doi.org/10.3390/ijms18112277
  • Kim, J.C., H.Y. Lee, M.H. Kim, H.J. Lee, H.Y. Kang & S.M. Kim, 2006. Preparation and characterization of chitosan/gelatin microcapsules containing triclosan. Colloids and Surfaces B: Biointerfaces, 52 (1): 52-56. https: //doi.org/10.1016/j.colsurfb.2006.07.001
  • Kladar, N.V., G.T. Anačkov, M.M. Rat, B.U. Srđenović, N.N. Grujić, E.I. Šefer & B.N. Božin, 2015. Biochemical characterization of Helichrysum italicum (Roth) G. Don subsp. italicum (Asteraceae) from Montenegro: phytochemical screening, chemotaxonomy, and antioxidant properties. Chemistry & Biodiversity, 12 (3): 419-431. https: //doi.org/10.1002/cbdv.201400174
  • Kose, S. & E. Ocak, 2020. Determination of antioxidant and antimicrobial activity of Herby cheese. Journal of Food Processing and Preservation, 44 (11): e14841. https://doi.org/10.1111/jfpp.14841
  • Leonardi, M., K.E. Ambryszewska, B. Melai, G. Flamini, P.L. Cioni, F. Parri & L. Pistelli, 2013. Essential‐oil composition of Helichrysum italicum (Roth) G. Don ssp. italicum from Elba Island (Tuscany, Italy). Chemistry & Biodiversity, 10 (3): 343-355.
  • Madene, A., M. Jacquot, J. Scher & S. Desobry, 2006. Flavour encapsulation and controlled release-a review. International Journal of Food Science & Technology, 41 (1): 1-21. https: //doi.org/10.1111/j.1365-2621.2005.00980.x
  • Mancini, E., L. De Martino, A. Marandino, M.R. Scognamiglio & V. De Feo, 2011. Chemical composition and possible in vitro phytotoxic activity of Helichrsyum italicum (Roth) Don ssp. italicum. Molecules, 16 (9): 7725-7735. https: //doi.org/10.3390/molecules16097725
  • Marfil, P.H.M., B.B. Paulo, I.D. Alvim & V.R. Nicoletti, 2018. Production and characterization of palm oil microcapsules obtained by complex coacervation in gelatin/gum arabic. Journal of Food Process Engineering, 41 (4): e12673. https: //doi.org/10.1111/jfpe.12673
  • Marfil, R., R. Giménez, O. Martínez, P.R. Bouzas, J.A. Rufián‐Henares, M. Mesías & C. Cabrera‐Vique, 2011. Determination of polyphenols, tocopherols and antioxidant capacity in virgin argan oil (Argania spinosa, skeels). European Journal of Lipid Science and Technology, 113 (7): 886-893. https: //doi.org/10.1002/ejlt.201000503
  • Martínez Rivas, C.J., M. Tarhini, W. Badri, K. Miladi, H. Greige-Gerges, Q.A. Nazari, S.A. Galindo Rodríguez, R.Á. Román, H. Fessi & A. Elaissari, 2017. Nanoprecipitation process: from encapsulation to drug delivery. International Journal of Pharmaceutics, 532 (1): 66-81. https: //doi.org/10.1016/j.ijpharm.2017.08.064
  • Martins, I.M., M.F. Barreiro, M. Coelho & A.E. Rodrigues, 2014. Microencapsulation of essential oils with biodegradable polymeric carriers for cosmetic applications. Chemical Engineering Journal, 245: 191-200. https: //doi.org/10.1016/j.cej.2014.02.024
  • Mastelić, J., O. Politeo & I. Jerković, 2008. Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don.-determination of ester bonded acids and phenols. Molecules, 13 (4): 795-803. https: //doi.org/10.3390/molecules13040795
  • Mastelic, J., O. Politeo, I. Jerkovic & N. Radosevic, 2005. Composition and antimicrobial activity of Helichrysum italicum essential oil and its terpene and terpenoid fractions. Chemistry of Natural Compounds, 41 (1): 35-40. https://doi.org/10.1007/s10600-005-0069-z
  • Moral, E., O. Bayram, E. Köksal, F. Danaş,& G.Ö.D.E. Fethiye, 2021. Kabak çekirdeği yağının kompleks koaservasyon yöntemi ile mikroenkapsülasyonu. Karaelmas Fen ve Mühendislik Dergisi, 11 (2): 91-97. https: //dergipark.org.tr/tr/pub/karaelmasfen/issue/66240/821902
  • Moukal, A., 2004. L’arganier, Argania spinosa L. (skeels), usage thérapeutique, cosmétique et alimentaire. Phytothérapie, 2 (5): 135-141. https: //doi.org/10.1007/s10298-004-0041-2
  • Ocak, B., 2012. Complex coacervation of collagen hydrolysate extracted from leather solid wastes and chitosan for controlled release of lavender oil. Journal of Environmental Management, 100: 22-28. https: //doi.org/10.1016/j.jenvman.2012.01.026
  • Öğretmen, Ö.Y., 2022. Scilla bifolia L. (Orman sümbülü) bitki kısımlarının antioksidan aktivitesinin belirlenmesi. Journal of Anatolian Environmental and Animal Sciences, 7 (1): 9-14. https: //doi.org/10.35229/jaes.980980
  • Patrickab, K.E., S. Abbasa, Y. Lva, I.S.B. Ntsamacd & X. Zhanga, 2013. Microencapsulation by complex coacervation of fish oil using gelatin/SDS/NaCMC. Pakistan Journal of Food Sciences, 23 (1): 17-25.
  • Peanparkdee, M., S. Iwamoto & R. Yamauchi, 2016. Microencapsulation: a review of applications in the food and pharmaceutical industries. Reviews in Agricultural Science, 4: 56-65. https: //doi.org/10.7831/ras.4.56
  • Piacentini, E., L Giorno, M.M. Dragosavac, G.T. Vladisavljević & R.G. Holdich, 2013. Microencapsulation of oil droplets using cold water fish gelatine/gum arabic complex coacervation by membrane emulsification. Food Research International, 53 (1): 362-372. https: //doi.org/10.1016/j.foodres.2013.04.012
  • Prata, A.S., M.H. Zanin, M.I. Ré & C.R. Grosso, 2008. Release properties of chemical and enzymatic crosslinked gelatin-gum arabic microparticles containing a fluorescent probe plus vetiver essential oil. Colloids and Surfaces B: Biointerfaces, 67 (2): 171-178. https: //doi.org/10.1016/j.colsurfb.2008.08.014
  • Rafińska, K., P. Pomastowski, J. Rudnicka, A. Krakowska, A. Maruśka, M. Narkute & B. Buszewski, 2019. Effect of solvent and extraction technique on composition and biological activity of Lepidium sativum extracts. Food Chemistry, 289: 16-25. https: //doi.org/10.1016/j.foodchem.2019.03.025
  • Raimundo, J.R., D.F. Frazão, J.L. Domingues, C. Quintela-Sabarís, T.P. Dentinho, O. Anjos & F. Delgado, 2018. Neglected Mediterranean plant species are valuable resources: the example of Cistus ladanifer. Planta, 248 (6): 1351-1364. https: //doi.org/10.1007/s00425-018-2997-4
  • Ree, R., N. Pellegrini, A. Protrggente, A. Pannala, M. Yang & C. Rice-Evans, 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Madicine, 26: 1231-1237. https: //doi.org/10.1016/S0891-5849 (98)00315-3
  • Renu, S., K. S. Shivashangari & V. Ravikumar, 2020. Incorporated plant extract fabricated silver/poly-D, l-lactide-co-glycolide nanocomposites for antimicrobial based wound healing. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 228: 117673. https: //doi.org/10.1016/j.saa.2019.117673
  • Rutz, J.K., C.D. Borges, R.C. Zambiazi, M.M. Crizel-Cardozo, L.S. Kuck & C.P. Noreña, 2017. Microencapsulation of palm oil by complex coacervation for application in food systems. Food Chemistry, 220: 59-66. https: //doi.org/10.1016/j.foodchem.2016.09.194
  • Saadi, B., F. Msanda & H. Boubaker, 2013. Contributions of folk medicine knowledge in Southwestern Morocco: the case of rural communities of imouzzer Ida outanane region. International Journal of Medicinal Plant Research, 2 (1): 135-145.
  • Sarkic, A. & I. Stappen, 2018. Essential oils and their single compounds in cosmetics-A critical review. Cosmetics, 5 (1): 11. https: //doi.org/10.3390/cosmetics5010011
  • Shaddel, R., J. Hesari, S. Azadmard-Damirchi, H. Hamishehkar, B. Fathi-Achachlouei & Q. Huang, 2018. Use of gelatin and gum arabic for encapsulation of black raspberry anthocyanins by complex coacervation. International Journal of Biological Macromolecules, 107: 1800-1810. https: //doi.org/10.1016/j.ijbiomac.2017.10.044
  • Strauss, G. & S.M. Gibson, 2004. Plant phenolics as cross-linkers of gelatin gels and gelatin-based coacervates for use as food ingredients. Food Hydrocolloids,18: 81-89. https: //doi.org/10.1016/S0268-005X (03)00045-6
  • Tichota, D.M., A.C. Silva, J.M.S. Lobo & M.H. Amaral, 2014. Design, characterization and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration. International Journal of Nanomedicine, 9: 3855. https: //doi.org/10.2147/IJN.S64008
  • Timilsena, Y.P., B. Wang, R. Adhikari, & B. Adhikari, 2017. Advances in microencapsulation of polyunsaturated fatty acids (PUFAs)-rich plant oils using complex coacervation: A review. Food Hydrocolloids, 69: 369-381. https://doi.org/10.1016/j.foodhyd.2017.03.007
  • Timilsena, Y.P., T.O. Akanbi, N. Khalid, B. Adhikari & C.J. Barrow, 2019. Complex coacervation: principles, mechanisms and applications in microencapsulation. International Journal of Biological Macromolecules, 121: 1276-1286. https: //doi.org/10.1016/j.ijbiomac.2018.10.144
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  • Viegas, D.A., A. Palmeira-de-Oliveira, L. Salgueiro, J. Martinez-de-Oliveira & R. Palmeira-de-Oliveira, 2014. Helichrysum italicum: from traditional use to scientific data. Journal of Ethnopharmacology, 151 (1): 54-65. https: //doi.org/10.1016/j.jep.2013.11.005
  • Xiao, Z., W. Liu, G. Zhu, R. Zhou & Y. Niu, 2014. A review of the preparation and application of flavour and essential oils microcapsules based on complex coacervation technology. Journal of the Science of Food and Agriculture, 94 (8): 1482-1494. https: //doi.org/10.1002/jsfa.6491
  • Yang, Y., M. Anvari, C.H. Pan & D. Chung, 2012. Characterisation of interactions between fish gelatin and gum arabic in aqueous solutions. Food Chemistry, 135 (2): 555-561. https: //doi.org/10.1016/j.foodchem.2012.05.018
  • Yıldız, Ş. & S. Turan, 2021. Timokinon, timol ve karvakrolün antioksidan aktiviteleri ve lipit oksidasyonunu önleme kapasiteleri. Atatürk Üniversitesi Ziraat Fakültesi Dergisi, 52 (1): 108-118. https: //doi.org/10.17097/ataunizfd.773499
  • Yiğit, A. & A. Gökçöl, 2021. Çeltik (Oryza sativa L.) tohumlarına uygulanabilecek vigor test yöntemlerinin optimizasyonu. Ege Üniversitesi Ziraat Fakültesi Dergisi, 58 (4): 599-612. https: //doi.org/10.20289/zfdergi.886497
  • Zaanoun, I., S. Gharby & I. Bakass, 2014. Kinetic parameter determination of roasted and unroasted argan oil oxidation under rancimat test conditions. Grasas y Aceites, 65 (3): e033-e033. https: //doi.org/10.3989/gya.122713
  • Zuanon, L.A.C., C.R. Malacrida & V.R.N Telis, 2013. Production of turmeric oleoresin microcapsules by complex coacervation with gelatin-gum arabic. Journal of Food Process Engineering, 36 (3): 364-373. https: //doi.org/10.1111/jfpe.12003
Toplam 64 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Ziraat, Veterinerlik ve Gıda Bilimleri
Bölüm Makaleler
Yazarlar

Gözde K. Erdoğan 0000-0002-7432-7466

Fethiye Göde 0000-0002-3008-1353

Proje Numarası FYL-2022-8645
Erken Görünüm Tarihi 29 Aralık 2022
Yayımlanma Tarihi 31 Aralık 2022
Gönderilme Tarihi 27 Mart 2022
Kabul Tarihi 6 Ağustos 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 59 Sayı: 4

Kaynak Göster

APA K. Erdoğan, G., & Göde, F. (2022). Altın otu (Helichrysum italicum) esansiyel yağının mikrokapsüle edilmesi ve karakterizasyonu. Journal of Agriculture Faculty of Ege University, 59(4), 669-684. https://doi.org/10.20289/zfdergi.1093914

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