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COVID-19'lu çocuklarda ABO ve Rh kan gruplarının dağılımı ile klinik seyir arasındaki ilişki

Year 2021, Volume: 7 Issue: 1, 32 - 37, 23.04.2021
https://doi.org/10.30569/adiyamansaglik.889914

Abstract

Amaç: Bu çalışma, ABO ve Rh kan gruplarının çocuklarda COVID-19 sıklığını ve semptom gelişimini etkileyip etkilemediğini araştırmayı amaçlamaktadır.
Gereç ve Yöntem: Çalışmaya SARS-CoV-2 PCR testi pozitif 337 çocuk ve kontrol grubu olarak 1286 sağlıklı çocuk dahil edildi.
Bulgular: Rh (+) çocuklarda hasta oranı, Rh (-) çocuklara göre anlamlı derecede yüksekti (p=0,006). Kan grubu A'nın, COVID-19 vakalarında semptom geliştirme için bir risk faktörü olduğu ve riski artırdığı bulunmuştur. Rh (+) kan grubunun COVID-19 için bağımsız bir risk faktörü olduğu ve COVID-19 vakalarının semptomatik olma oranını artırdığı bulunmuştur.
Sonuç: Çalışmamızdan elde edilen veriler, Rh pozitifliğinin çocukları hem COVID-19'a hem de COVID-19 durumunda semptomların gelişimine duyarlı hale getirdiğini ve kan grubu A'nın COVID-19 pozitif çocuklarda semptom geliştirme riskini artırdığını göstermektedir.

Supporting Institution

Yok

Project Number

Yok

Thanks

Laboratuvar çalışanları ve sorumlularına çok teşekkür ederim.

References

  • Sankar J, Dhochak N, Kabra SK, Lodha R. COVID-19 in Children: Clinical Approach and Management. Indian J Pediatr. 2020;87(6):433-442.
  • Tezer H, Bedir Demirdağ T. Novel coronavirus disease (COVID-19) in children. Turk J Med Sci. 2020;50(SI-1):592-603.
  • AbdelMassih AF, Mahrous R, Taha A, Saud A, Osman A, Kamel B, et al. The potential use of ABO blood group system for risk stratification of COVID-19. Med Hypotheses. 2020;145:110343.
  • Fan Q, Zhang W, Li B, Li DJ, Zhang J, Zhao F. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. Front Cell Infect Microbiol. 2020;10:404.
  • Wu BB, Gu DZ, Yu JN, Yang J, Shen WQ. Association between ABO blood groups and COVID-19 infection, severity and demise: A systematic review and meta-analysis. Infect Genet Evol. 2020;84:104485.
  • Abdollahi A, Mahmoudi-Aliabadi M, Mehrtash V, Jafarzadeh B, Salehi M. The Novel Coronavirus SARS-CoV-2 Vulnerability Association with ABO/Rh Blood Types. Iran J Pathol. 2020;15(3):156-160.
  • Rahim F, Amin S, Bahadur S, Noor M, Mahmood A, Gul H. ABO / Rh-D Blood types and susceptibility to Corona Virus Disease-19 in Peshawar. Pakistan. Pak J Med Sci. 2021;37(1):4-8.
  • Bhandari P, Durrance RJ, Bhuti P, Salama C. Analysis of ABO and Rh Blood Type Association With Acute COVID-19 Infection in Hospitalized Patients: A Superficial Association Among a Multitude of Established Confounders. J Clin Med Res. 2020;12(12):809-815.
  • Latz CA, DeCarlo C, Boitano L, Png CYM, Patell R, Conrad MF, Eagleton M, Dua A. Blood type and outcomes in patients with COVID-19. Ann Hematol. 2020;99(9):2113-2118.
  • Zietz M, Zucker J, Tatonetti NP. Testing the association between blood type and COVID-19 infection, intubation, and death. medRxiv [Preprint]. 2020 Apr 11:2020.04.08.20058073.
  • Niles JK, Karnes HE, Dlott JS, Kaufman HW. Association of ABO/Rh with SARS-CoV-2 positivity: The role of race and ethnicity in a female cohort. Am J Hematol. 2021;96(1):E23-E26.
  • Dzik S, Eliason K, Morris EB, Kaufman RM, North CM. COVID-19 and ABO blood groups. Transfusion. 2020;60(8):1883-1884.
  • Wu Y, Feng Z, Li P, Yu Q. Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19. Clin Chim Acta. 2020;509:220-223.
  • Zaidi FZ, Zaidi ARZ, Abdullah SM, Zaidi SZA. COVID-19 and the ABO blood group connection. Transfus Apher Sci. 2020;59(5):102838.
  • Zhao J, Yang Y, Huang H, Li D, Gu D, Lu X, et al. Relationship between the ABO Blood Group and the COVID-19 Susceptibility. Clin Infect Dis. 2020 Aug 4:ciaa1150.
  • Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, et al. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19. Blood Adv. 2020;4(20):4981-4989.
  • Padhi S, Suvankar S, Dash D, Panda VK, Pati A, Panigrahi J, Panda AK. ABO blood group system is associated with COVID-19 mortality: An epidemiological investigation in the Indian population. Transfus Clin Biol. 2020;27(4):253-258.
  • Dai X. ABO blood group predisposes to COVID-19 severity and cardiovascular diseases. Eur J Prev Cardiol. 2020;27(13):1436-1437.

The relationship between the distribution of ABO and Rh blood groups and the clinical course in children with COVID-19

Year 2021, Volume: 7 Issue: 1, 32 - 37, 23.04.2021
https://doi.org/10.30569/adiyamansaglik.889914

Abstract

Aim: This study aims to investigate whether ABO and Rh blood groups affect the prevalence and symptom development of COVID-19 in children.
Materials and Methods: The study included 337 children with positive SARS-CoV-2 PCR test and 1286 healthy children as control group.
Results: The rate of patients in Rh (+) children was significantly higher than in Rh (-) children (p=0.006). Blood type A has been found to be a risk factor for developing symptoms in COVID-19 cases and increases the risk. It has been found that the Rh (+) blood group is an independent risk factor for COVID-19 and increases the rate of being symptomatic of COVID-19 cases.
Conclusion: The findings of our study show that Rh positivity renders children sensitive to the development of clinical symptoms both against COVID-19 and in the case of COVID-19, and blood type A increases the risk of developing symptoms in children with COVID-19.

Project Number

Yok

References

  • Sankar J, Dhochak N, Kabra SK, Lodha R. COVID-19 in Children: Clinical Approach and Management. Indian J Pediatr. 2020;87(6):433-442.
  • Tezer H, Bedir Demirdağ T. Novel coronavirus disease (COVID-19) in children. Turk J Med Sci. 2020;50(SI-1):592-603.
  • AbdelMassih AF, Mahrous R, Taha A, Saud A, Osman A, Kamel B, et al. The potential use of ABO blood group system for risk stratification of COVID-19. Med Hypotheses. 2020;145:110343.
  • Fan Q, Zhang W, Li B, Li DJ, Zhang J, Zhao F. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. Front Cell Infect Microbiol. 2020;10:404.
  • Wu BB, Gu DZ, Yu JN, Yang J, Shen WQ. Association between ABO blood groups and COVID-19 infection, severity and demise: A systematic review and meta-analysis. Infect Genet Evol. 2020;84:104485.
  • Abdollahi A, Mahmoudi-Aliabadi M, Mehrtash V, Jafarzadeh B, Salehi M. The Novel Coronavirus SARS-CoV-2 Vulnerability Association with ABO/Rh Blood Types. Iran J Pathol. 2020;15(3):156-160.
  • Rahim F, Amin S, Bahadur S, Noor M, Mahmood A, Gul H. ABO / Rh-D Blood types and susceptibility to Corona Virus Disease-19 in Peshawar. Pakistan. Pak J Med Sci. 2021;37(1):4-8.
  • Bhandari P, Durrance RJ, Bhuti P, Salama C. Analysis of ABO and Rh Blood Type Association With Acute COVID-19 Infection in Hospitalized Patients: A Superficial Association Among a Multitude of Established Confounders. J Clin Med Res. 2020;12(12):809-815.
  • Latz CA, DeCarlo C, Boitano L, Png CYM, Patell R, Conrad MF, Eagleton M, Dua A. Blood type and outcomes in patients with COVID-19. Ann Hematol. 2020;99(9):2113-2118.
  • Zietz M, Zucker J, Tatonetti NP. Testing the association between blood type and COVID-19 infection, intubation, and death. medRxiv [Preprint]. 2020 Apr 11:2020.04.08.20058073.
  • Niles JK, Karnes HE, Dlott JS, Kaufman HW. Association of ABO/Rh with SARS-CoV-2 positivity: The role of race and ethnicity in a female cohort. Am J Hematol. 2021;96(1):E23-E26.
  • Dzik S, Eliason K, Morris EB, Kaufman RM, North CM. COVID-19 and ABO blood groups. Transfusion. 2020;60(8):1883-1884.
  • Wu Y, Feng Z, Li P, Yu Q. Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19. Clin Chim Acta. 2020;509:220-223.
  • Zaidi FZ, Zaidi ARZ, Abdullah SM, Zaidi SZA. COVID-19 and the ABO blood group connection. Transfus Apher Sci. 2020;59(5):102838.
  • Zhao J, Yang Y, Huang H, Li D, Gu D, Lu X, et al. Relationship between the ABO Blood Group and the COVID-19 Susceptibility. Clin Infect Dis. 2020 Aug 4:ciaa1150.
  • Hoiland RL, Fergusson NA, Mitra AR, Griesdale DEG, Devine DV, Stukas S, et al. The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19. Blood Adv. 2020;4(20):4981-4989.
  • Padhi S, Suvankar S, Dash D, Panda VK, Pati A, Panigrahi J, Panda AK. ABO blood group system is associated with COVID-19 mortality: An epidemiological investigation in the Indian population. Transfus Clin Biol. 2020;27(4):253-258.
  • Dai X. ABO blood group predisposes to COVID-19 severity and cardiovascular diseases. Eur J Prev Cardiol. 2020;27(13):1436-1437.
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Research Article
Authors

Mehmet Gündüz 0000-0003-4479-3404

Hayrettin Temel 0000-0002-6490-4530

Project Number Yok
Publication Date April 23, 2021
Submission Date March 3, 2021
Acceptance Date April 6, 2021
Published in Issue Year 2021 Volume: 7 Issue: 1

Cite

AMA Gündüz M, Temel H. COVID-19’lu çocuklarda ABO ve Rh kan gruplarının dağılımı ile klinik seyir arasındaki ilişki. ADYÜ Sağlık Bilimleri Derg. April 2021;7(1):32-37. doi:10.30569/adiyamansaglik.889914