Prenatal dönemleri boyunca günde bir saat kesintisiz 900 MHz elektromanyetik alan etkisine maruz kalan 75 günlük Sprague Dawley dişi sıçanların böbrek ve mesane dokularının histopatolojik olarak incelenmesi

Year 2022, Volume: 8 Issue: 2, 142 - 150, 30.08.2022

Sibel Türedi , Hatice Hancı , Ersan Odaci , Hakim Çelik

https://doi.org/10.30569/adiyamansaglik.1023728

Cited By: 1

Abstract

Amaç: Prenatal dönemde 900 MHz elektromanyetik alan (EMA) maruziyetinin sıçanların postnatal erişkinlik döneminde böbrek ve mesane dokuları üzerine etkileri araştırılmıştır.
Gereç ve Yöntem: 18 adet dişi sıçan; kontrol, Sham ve EMA olarak üç gruba ayrıldı. EMA grubu, prenatal dönem boyunca 1 saat/gün 900 MHz EMA'ya maruz bırakıldı; Sham grubu gebe sıçanlar EMA sistemi kapalı kafeste tutuldu. Kontrol grubu gebe sıçanlara ve postnatal yeni doğanlara uygulama yapılmadı. Deney süresi bitiminde böbrek ve mesane dokuları histopatolojik olarak değerlendirildi.
Bulgular: Kontrol ve Sham gruplarının böbrek ve mesane örneklerinin normal morfolojide olduğu, EMA grubunda böbrekte tübüler ve glomerular hasar, bowman boşluğunda dilatasyon; mesane ürotelyum epitelinde dejenerasyon izlendi.
Sonuç: Prenatal dönemde 900 MHz EMA maruziyeti, erişkinlikte yavru sıçanların böbrek ve mesane dokusunda ciddi histopatolojik değişimlerin olabileceği kanaatindeyiz.

Keywords

Böbrek, Mesane, Elektromanyetik Alan, Histopatoloji, Sıçan

A histopathological examination of kidney and bladder tissues of 75-day female Sprague Dawley rats exposed to a one-hour continuous 900 MHz electromagnetic field during the prenatal period

Abstract

Aim: The effects on kidney and bladder tissues in postnatal adulthood in rats exposed to 900 MHz electromagnetic field (EMF) in the prenatal period were investigated
Materials and Methods: Eighteen female rats; were divided into three groups, control, sham and EMF. The EMF group was exposed to 900 MHz EMF for 1 hour/day during the prenatal period. Sham group pregnant rats were kept in the EMF system closed cage. No procedure was performed on the control pregnant group rats and postnatal newborns. At the end of the experimental period, kidney and bladder tissues were evaluated histopathologically.
Results: Kidney and bladder specimens from the control and sham groups exhibited a normal morphological structure. Tubular and glomerular damage, dilatation in Bowman's space in kidney tissue and degeneration of the urothelial epithelium in the bladder were observed in the EMF group.
Conclusion: We think that exposure to 900 MHz EMF during the prenatal period may cause severe histopathological changes in kidney and bladder tissue in adulthood.

Keywords

Kidney, Bladder, Electromagnetic field, Adulthood, Histopathology, Rat

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