Review
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Year 2023, Volume: 5 Issue: 1, 49 - 58, 30.04.2023
https://doi.org/10.59124/guhes.1217060

Abstract

Project Number

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References

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  • Ahmadi, M., Scurtu, M., Filimon, N., Mederle, N., Tulcan, C., Milovanov, C., . . . Mircu, C. (2017). Colostrum a natural valuable product for new-born animal and industry. Lucrari Stiintifice-Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 50(1), 5-16. https://doi.org/10.13140/RG.2.2.11719.04003
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  • Alsharnoubi, J., Ishaak, M., Elsheikh, S., & Ezzat, S. (2019). Transforming growth factor beta-1 in human breast milk and its correlation with infants' parameters. Breastfeeding Medicine, 14(6), 404-407. https://doi.org/10.1089/bfm.2018.0214
  • Alzaree, F. A., AbuShady, M. M., Atti, M. A., Fathy, G. A., Galal, E. M., Ali, A., & Elias, T. R. (2019). Effect of early breast milk nutrition on serum insulin-like growth factor-1 in preterm infants. Open Access Macedonian Journal of Medical Sciences, 7(1), 77. https://doi.org/10.3889/oamjms.2019.035
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  • Cheng, L., Kiewiet, M.B.G., Groeneveld, A., Nauta, A., & de Vos, P. (2019). Human milk oligosaccharides and its acid hydrolysate LNT2 show immunomodulatory effects via TLRs in a dose and structure dependent way. Journal of Functional Foods, 59 (March):174–84. https://doi.org/10.1016/j.jff.2019.05.023
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  • Dror, D. K., & Allen, L. H. (2018). Vitamin B-12 in human milk: a systematic review. Advances in nutrition, 9(suppl_1), 358S-366S. https://doi.org/10.1093/advances/nmx019
  • El-Loly, M. M. (2019). Immune Defenses of Colostrum and Milk in Human and Animals. Advanced Research in Gastroenterology & Hepatology. https://doi.org/10.19080/ARGH.2019.12.555832
  • El-Loly, M. M. (2022a). Colostrum ingredients, its nutritional and health benefits-an overview. Clinical Nutrition Open Science. https://doi.org/10.1016/j.nutos.2022.07.001
  • El-Loly, M. M. (2022b). Evaluation of Colostrum Quality-A Narrative Brief Overview. International Journal of Immunology, 10(2), 19-24. https://doi.org/10.11648/j.iji.20221002.12
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A Brief Overview: Breast Milk Colostrum Bioactives

Year 2023, Volume: 5 Issue: 1, 49 - 58, 30.04.2023
https://doi.org/10.59124/guhes.1217060

Abstract

Colostrum is the basic nutrient that is secreted after birth and meets all the needs of the newborn. Colostrum is rich in nutritional micro and macronutrients and bioactive substances such as antimicrobial and growth factors, which are necessary for the development of the newborn's digestive and immune systems. Colostrum differs from mature milk in terms of appearance, amount, and content. It has higher levels of immunoglobulin A, growth factors, and other protective components. Colostrum has a lesser energy, protein, and carbohydrate composition than mature milk, but a higher fat content. This review summarizes the available information on the composition of human colostrum. Furthermore, it provides an overview of growth factors and immune factors found in colostrum.

Supporting Institution

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Project Number

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Thanks

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References

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  • Ahmadi, M., Scurtu, M., Filimon, N., Mederle, N., Tulcan, C., Milovanov, C., . . . Mircu, C. (2017). Colostrum a natural valuable product for new-born animal and industry. Lucrari Stiintifice-Universitatea de Stiinte Agricole a Banatului Timisoara, Medicina Veterinara, 50(1), 5-16. https://doi.org/10.13140/RG.2.2.11719.04003
  • Ahmed, L., Islam, S. N., Khan, M. N. I., Huque, S., & Ahsan, M. (2004). Antioxidant micronutrient profile (vitamin E, C, A, copper, zinc, iron) of colostrum: association with maternal characteristics. Journal of tropical pediatrics, 50(6), 357-358. https://doi.org/10.1093/tropej/50.6.357
  • Alsharnoubi, J., Ishaak, M., Elsheikh, S., & Ezzat, S. (2019). Transforming growth factor beta-1 in human breast milk and its correlation with infants' parameters. Breastfeeding Medicine, 14(6), 404-407. https://doi.org/10.1089/bfm.2018.0214
  • Alzaree, F. A., AbuShady, M. M., Atti, M. A., Fathy, G. A., Galal, E. M., Ali, A., & Elias, T. R. (2019). Effect of early breast milk nutrition on serum insulin-like growth factor-1 in preterm infants. Open Access Macedonian Journal of Medical Sciences, 7(1), 77. https://doi.org/10.3889/oamjms.2019.035
  • Bagwe-Parab, S., Yadav, P., Kaur, G., Tuli, H. S., & Buttar, H. S. (2020). Therapeutic applications of human and bovine colostrum in the treatment of gastrointestinal diseases and distinctive cancer types: The current evidence. Frontiers in Pharmacology, 11, 01100. https://doi.org/10.3389/fphar.2020.01100
  • Ballard, O., & Morrow, A. L. (2013). Human milk composition: nutrients and bioactive factors. Pediatric Clinics, 60(1), 49-74. https://doi.org/10.1016/j.pcl.2012.10.002
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  • Cheng, L., Akkerman, R., Kong, C., Walvoort, M.T.C., & de Vos, P. (2021). More than sugar in the milk: human milk oligosaccharides as essential bioactive molecules in breast milk and current insight in beneficial effects, Critical Reviews in Food Science and Nutrition, 61:7, 1184-1200, https://doi.org/10.1080/10408398.2020.1754756
  • Cheng, L., Kiewiet, M.B.G., Groeneveld, A., Nauta, A., & de Vos, P. (2019). Human milk oligosaccharides and its acid hydrolysate LNT2 show immunomodulatory effects via TLRs in a dose and structure dependent way. Journal of Functional Foods, 59 (March):174–84. https://doi.org/10.1016/j.jff.2019.05.023
  • Chrustek, A., Dombrowska-Pali, A., & Olszewska-Słonina, D. (2021). Analysis of the composition and antioxidant status of breast milk in women giving birth prematurely and on time. PLoS One, 16(7), e0255252. https://doi.org/10.1371/journal.pone.0255252
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  • Demers-Mathieu, V., Huston, R. K., Markell, A. M., McCulley, E. A., Martin, R. L., Spooner, M., & Dallas, D. C. (2019). Differences in maternal immunoglobulins within mother’s own breast milk and donor breast milk and across digestion in preterm infants. Nutrients, 11(4), 920. https://doi.org/10.3390/nu11040920
  • Dror, D. K., & Allen, L. H. (2018). Vitamin B-12 in human milk: a systematic review. Advances in nutrition, 9(suppl_1), 358S-366S. https://doi.org/10.1093/advances/nmx019
  • El-Loly, M. M. (2019). Immune Defenses of Colostrum and Milk in Human and Animals. Advanced Research in Gastroenterology & Hepatology. https://doi.org/10.19080/ARGH.2019.12.555832
  • El-Loly, M. M. (2022a). Colostrum ingredients, its nutritional and health benefits-an overview. Clinical Nutrition Open Science. https://doi.org/10.1016/j.nutos.2022.07.001
  • El-Loly, M. M. (2022b). Evaluation of Colostrum Quality-A Narrative Brief Overview. International Journal of Immunology, 10(2), 19-24. https://doi.org/10.11648/j.iji.20221002.12
  • Espinosa-Martos, I., Montilla, A., Segura, A. G. d., Escuder, D., Bustos, G., Pallás, C., . . . Fernández, L. (2013). Bacteriological, Biochemical, and Immunological Modifications in Human Colostrum After Holder Pasteurisation. Journal of Pediatric Gastroenterology and Nutrition, 56(5), 560-568. https://doi.org/10.1097/MPG.0b013e31828393ed
  • Finley, D. A., Lönnerdal, B., Dewey, K. G., & Grivetti, L. E. (1985). Breast milk composition: fat content and fatty acid composition in vegetarians and non-vegetarians. Am J Clin Nutr, 41(4), 787-800. https://doi.org/10.1093/ajcn/41.4.787
  • Giansanti, F., Panella, G., Leboffe, L., & Antonini, G. (2016). Lactoferrin from milk: Nutraceutical and pharmacological properties. Pharmaceuticals, 9(4), 61.
  • Gila-Diaz, A., Arribas, S. M., Algara, A., Martín-Cabrejas, M. A., López de Pablo, Á. L., Sáenz de Pipaón, M., & Ramiro-Cortijo, D. (2019). A review of bioactive factors in human breastmilk: a focus on prematurity. Nutrients, 11(6), 1307. https://doi.org/10.3390/nu11061307
  • Grilo, E. C., Lira, L. Q. D., Dimenstein, R., & Ribeiro, K. D. D. S. (2013). Influence of prematurity and birth weight on the concentration of α-tocopherol in colostrum milk. Revista Paulista de Pediatria, 31, 473-479.
  • Godhia, M. L., & Patel, N. (2013). Colostrum–its Composition, Benefits as a Nutraceutical–A Review. Current Research in Nutrition and Food Science Journal, 1(1), 37-47. https://dx.doi.org/10.12944/CRNFSJ.1.1.04
  • Hoppu, U., Isolauri, E., Laakso, P., Matomäki, J., & Laitinen, K. (2012). Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines. European Journal of Nutrition, 51(2), 211-219. https://dx.doi.org/10.1007/s00394-011-0209-0
  • Karakaya Suzan, Ö. (2020). Kolostrum: Özellikleri ve prematüre bebeğe faydaları. Sürekli Tıp Eğitimi Dergisi, 29(3), 221-227. https://doi.org/10.17942/sted.541754
  • Khaleva, E., Gridneva, Z., Geddes, D. T., Oddy, W. H., Colicino, S., Blyuss, O., . . . Munblit, D. (2019). Transforming growth factor beta in human milk and allergic outcomes in children: A systematic review. Clinical & Experimental Allergy, 49(9), 1201-1213. https://doi.org/10.1111/cea.13409
  • Kong, C., Elderman, M., Cheng, L., de Haan, B.J., Nauta, N., & de Vos, P. (2019). Modulation of intestinal epithelial glycocalyx development by human milk oligosaccharides and non-digestible carbohydrates. Molecular Nutrition & Food Research, 63 (17):1900303. https://doi.org/10.1002/mnfr.201900303
  • Li, M., Chen, J., Shen, X., Abdlla, R., Liu, L., Yue, X., & Li, Q. (2022). Metabolomics-based comparative study of breast colostrum and mature breast milk. Food Chemistry, 384, 132491. https://doi.org/10.1016/j.foodchem.2022.132491
  • Lima, M. S., Dimenstein, R., & Ribeiro, K. D. (2014). Vitamin E concentration in human milk and associated factors: a literature review. Jornal de pediatria, 90, 440-448.
  • Lönnerdal, B. (2013). Bioactive proteins in breast milk. Journal of paediatrics and child health, 49, 1-7. https://doi.org/10.1111/jpc.12104
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There are 56 citations in total.

Details

Primary Language English
Subjects Nutrition and Dietetics
Journal Section Araştırma Makalesi
Authors

Çağla Ayer 0000-0001-6124-7339

Pakize Eylem Şeker Arı 0000-0002-6651-5379

Gulcin Sagdicoglu Celep 0000-0002-4598-5814

Project Number -
Publication Date April 30, 2023
Published in Issue Year 2023 Volume: 5 Issue: 1

Cite

APA Ayer, Ç., Şeker Arı, P. E., & Sagdicoglu Celep, G. (2023). A Brief Overview: Breast Milk Colostrum Bioactives. Journal of Gazi University Health Sciences Institute, 5(1), 49-58. https://doi.org/10.59124/guhes.1217060