Chemical compositions and antimicrobial activity of Prunella vulgaris L.

Year 2018, Volume: 2 Issue: Special 1, 186 - 189, 07.10.2018

Nagehan Saltan , Damla Kırıcı , Yavuz Bülent Köse , Betül Demirci

https://doi.org/10.31015/jaefs.18032

Abstract

The popular
medicinal plant Prunella vulgaris L., (Lamiaceae) is a
perennial and an edible herbaceous plant which is widely distributed
in the temperate zone and tropical mountains of Europe and Asia. Due to its
medicinal and industrial importance, the demand for P. vulgaris has
increased steadily in recent years. In the present study, the volatile compounds of the P. vulgaris
were accumulated by Headspace-Solid Phase Microextraction (HS-SPME) technique,
and, analysed by gas chromatography/mass spectrometry (GC/MS). The chemical
composition of the methanolic extract (ME) and infusion (INF) of P. vulgaris were determined. Aerial parts of P. vulgaris INF
of the major compounds were found hexanal (23.1%), ionol (10.7%), (Z)-3-hexenal (3.2%) and 3,5-octadien-2-one.
The ME of P. vulgaris were
characterized with α-fenchone (11.1%), hexanal (8.2%),
3,5-octadien-2-one (4.7%), methyl benzoate (4.5%) and selina-4,11-diene (3.1%).
 It was evaluated the antimicrobial activity of
P. vulgaris extracts (ME, INF) in in vitro conditions against different
kinds of microorganisms. The
INF showed weak antimicrobial activity Minimum Inhibitor Concentration (MIC) against all tested
microorganisms whereas ME showed weak antimicrobial effects E. coli, S. aureus and Pseudomonas
aeruginosa; S. pyogenes (20 mg / mL) and C. albicans (15 mg /
mL). 

Keywords

Prunella vulgaris, HS-SPME, Volatile compound, Antimicrobial activity

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