Relationship between mean platelet volume and intensive care unit requirement in COVID-19 patients

Year 2021, Volume: 4 Issue: 3, 353 - 357, 21.05.2021

Rohat Ak , Fatih Doğanay

https://doi.org/10.32322/jhsm.909574

Cited By: 2

Abstract

Objective: Our aim in this study is to examine the relationship between the mean platelet volume (MPV) and the intensive care unit (ICU) requirement in patients with 2019 coronavirus disease (COVID-19).
Methods: This retrospective observational study was conducted with patients who were diagnosed with COVID-19 in the emergency department of a tertiary hospital. The study was continued with the remaining 711 patients after using the inclusion and exclusion criteria. CHAID analysis was used as the decision tree method in analyzing the data. The relationship between ICU requirement and MPV were evaluated.
Results: There were 711 patients included in this study. The median age of the population was 64 (49-76). According to the CHAID analysis, the study population was divided into 2 classes as those who aged 58 years or younger (Younger Group) and those who older than 58 years (Older Group), and the relationship between the 8.3 threshold value of MPV and the ICU requirement was analyzed. For the Younger group, a significant difference was found in terms of ICU requirement based on the 8.3 threshold value of MPV.
Conclusion: Advanced age, high MPV and PLT values in COVID-19 patients, are associated with the ICU requirement. The 8.3 threshold value of MPV can be used as one of the parameters determining the ICU requirement in relatively young patients. In the geriatric age group, it is not beneficial to use MPV measurement to assign the ICU requirement. Multi-center studies with a large number of patients are needed to present the strength of the results of our study more clearly.

Keywords

COVID-19, mean platelet volume, intensive care unit, platelet count, CHAID

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