Effect of SARS-CoV-2 pandemic on breast cancer stage at diagnosis

Year 2022, Volume: 5 Issue: 1, 62 - 66, 17.01.2022

Murat Bulut Özkan , Murat Baki Yıldırım , Ramazan Topcu , Veysel Barış Turhan

https://doi.org/10.32322/jhsm.1005604

Abstract

Objective: We aimed to research the effects of the COVID-19 pandemic on breast cancer stages at the time of diagnosis.
Material and Method: The data of female patients over 18 who underwent breast surgery and sentinel lymph node sampling for malignancy between 01.06.2019 and 31.11.2019 with between 01.06.2020 and 31.11.2020 were analyzed. Patients were divided into two groups as before and during the pandemic.
Results: Data of 55 patients in total were reached, of which 31 were diagnosed before the pandemic and 24 after the pandemic. There is no significant difference between the two groups in terms of age. Average tumor size is 3.42±2.00 cm, and 18 patient (32.7%) has positive sentinel lymph node biopsy (SLNB). In before pandemic group (Group 1) SLNB positivity rate is only 25.8% (n=8) but in during pandemic group (Group 2) this rate reaches 41.7% (n=10), but this is not statistically significant(p=0.214). While the tumor size of the patients in Group 1 was 3.35±2.25 cm, it was 3.51±1.67 cm in Group 2. Still, no statistically significant difference was observed (p=0.141).
Conclusion: As a result of our study, although statistically insignificant, an increase in tumor sizes and positive lymph node numbers was detected. We predict that statistically significant results will be obtained in studies with a larger number of cases.

Keywords

covid-19, breast cancer, sentinel lymp node, prognosis

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