Bakterilerde glutatyon ve önemi

Nihal Kanat; Serap Akdemir

doi:10.16984/saufbed.15609

Research Article

-

Year 2014, Volume: 18 Issue: 2, 111 - 117, 17.07.2014

Nihal Kanat , Serap Akdemir

https://doi.org/10.16984/saufbed.15609

Cited By: 1

Abstract

Glutathione is a tripeptide which consisted of glutamate, cysteine and glycine. As well as eukaryotic organisms, some prokaryotes produce this compound and it functions as a protector of the cell against to unfavorable environmental stresses mainly oxidative stress. When bacteria encounter to a sub-lethal stress, they gain resistance to mentioned stress and then the processes used to control pathogenic bacteria may become ineffective. Therefore, it is important to know the properties and functions of glutathione which have a key role in protection from stress in bacteria.

Keywords

Glutathione, bacterium, oxidative stress, pH, chlorine

References

(REFERENCES) Smirnova, G.V., Oktyabrsky, O.N. (2005) Glutathione in Bacteria, Biochemistry (Moscow), 70 (11), 1199-1211.
Masip, L., Veeravalli, K., Georgiou, G. (2006) The Many Faces of Glutathione in Bacteria, Antioxidants & Redox Signaling, 8 (5-6), 753– 7
Dikici, A. (2009) Çevresel Stres Faktörlerine Karşı Bakteriyel Adaptasyonlar ve Mekanizmaları, Gıda Teknolojileri Elektronik Dergisi, Cilt: 4, No: 3, 59-68.
Ray, B. (2004) Microbial stress response in the food environment. “Fundamental Food Microbiology”, 3 rd edn, CRC press LLC., New York, pp.103-121.
Yousef, A.E., Courtney, P.D. (2003) Basics of stress adaptation and implications in newgeneration foods. “Microbial Stress Adaptation and Food Safety” A.E. Yousef and V.K. Juneja (Editörler). CRC Pres, New York. Syf:1–25.
Arsene, F., Tomoyasu, T., Bukau, B. (2000) The heat shock response of Escherichia coli, International Food Microbiology, 55:3-9.
Neidhardt, F.C., Vanbogelen, R.A. (2000) Proteomic analysis of bacterial stress response, in Bacterial Stress Responses. G. Storz and R. Hengge-Aronis, Eds. Washington, DC.: American Society for Microbiology Press, pp. 445-4
Cronan, J.E. (2002) Phospholipid modifications in bacteria, Current Opinion in Microbiology, 5, 202-20
Fahey, R.C., Brown, W.C., Adams, W.B., Worsham, M.B. (1978) Occurrence of glutathione in bacteria, Journal of Bacteriology, 133, 1126–1129.
Copley, S.D., Dhillon, J.K. (2002) Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes, Genome Biology, 3, 1–16.
Sareen, D., Newton, G.L., Fahey, R.C., Buchmeier, N.A. (2003) Mycothiol is essential for growth of Mycobacterium tuberculosis
Erdman. Journal of Bacteriology, 185 (22), 6736-6740.
Newton, G.L., Rawat, M.L.A., Clair J.J., Jothivasan, V.K., Budiarto, T., Hamilton C.J., Claiborne, A., Helmann, J.D., Fahey, R.C. (2009) Bacillithiol is an antioxidant thiol produced in Bacilli. Nature Chemical Biology, 5 (9), 625-627.
Meister, A. (1983) Selective modification of glutathione metabolism, Science, 220, 472–477.
Aslund, F., Berndt, K.D., Homgren A. (1997)
Redox potentials of glutaredoxins and other thiol-disulfide oxidoreductases of the thioredoxin superfamily determined by direct protein-protein redox equilibria, Journal of Biological Chemistry, 272, 30780–30786.
She, Z.W., Mays, D.C., Sagone, A.L., Davis, W.B. (1997) Aminobenzoic acid compounds as
HOCl traps for activated neutrophils, Free Radical Biology and Medicine, 22, 989–998. Ziegler, D.M. (1985) Role of reversible oxidation-reduction of enzyme thiols-disulfides in metabolic regulation, Annual Review of Biochemistry, 54, 305-329.
Arrick B.A., Nathan C.F. (1984) Glutathion metabolism as a determinant of the therapeutic efficacy, Cancer Research, 44, 4224-4232.
Demirkol, O., Ercal, N. (2012) Glutathione, In: Handbook of Analysis of Active Compounds in
Functional Foods, Editors: L.M.L. Nollet, F. Toldra, CRC Press, Taylor & Francis, 978-14398-1588-5, pp.69-86.
Meister, A., Anderson, M.E. (1983) Glutathione.
Annual Review of Biochemistry, 52: 711-760. Schafer, F.Q., Buettner, G.R. (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple, Free Radical
Biology and Medicine, 30 (11), 1191–1212.
Meister, A. (1988) Glutathione metabolism and its selective modification. Journal of Biological Chemistry, 263, 17205–17208.
Smirnova G.V., Torkhova O.A., Oktyabrsky, O.N. (2003) The Status and the Role of
Glutathione under Disturbed Ionic Balance and pH Homeostasis in Escherichia coli, Microbiology, 72 (5), 542–547. Moat, G.A., Foster, W., Spector, J., Michael, P. (2002) Microbial Physiology, ISBN: 0-47139483-1, Wiley-Liss.
Mate´S, J.M. (2000) Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology, Toxicology, 153, 83–
Kulaksiz, C.B., Dalmızrak, O, Ogus, I.H., Ozer, N. (2010) Purification and characterisation of rat kidney glutathione reductase, The Protein Journal, 29 (4), 250-256.
Smirnova, G.V., Zakirova, O.N., Oktyabrsky, O.N. (2001) The Role of Antioxidant Systems in the Response of Escherichia coli to Heat Shock. Microbiology, 70 (5), 512–518.
Mclaggan, D., Logan, T.M., Lynn, D.G., Epstein, W. (1990) Involvement of gammaglutamyl peptides in osmoadaptation of Escherichia coli. Journal of Bacteriology, 172, 3631–3636.
Smirnova, G.V., Muzyka, N.G., Oktyabrsky, O.N. (2000) The role of antioxidant enzymes in response of Escherichia coli to osmotic upshift. FEMS Microbiology Letters, 186, 209–213.
Ferguson, G.P., Booth, I.R. (1998) Importance of Glutathione for Growth and Survival of Escherichia coli cells: Detoxification of Methylglyoxal and Maintenance of Intracellular K + . Journal of Bacteriology, 180, 4314–4318.
Scatina, J., Abdel-Rahman, M.S., Goldman, E. (1985) The inhibitory effect of Alcide, an antimicrobial drug, on protein synthesis in Escherichia coli, Journal of Applied Toxicology, 5, 388–394.
Luppens, S.B., Barbaras, B., Breeuwer, P., Rombouts, F.M., Abee, T. (2003) Selection of fluorescent probes for flow cytometric viability assessment of Listeria monocytogenes exposed to membrane-active and oxidizing disinfectants.
Journal of Food Protection, 66, 1393–1401.
Sander, J.E., Wilson, J.L. (1999) Effect of
Hydrogen Peroxide disinfection during incubation of chicken eggs on microbial levels and productivity, Avian Diseases, 43, 227-233. Sapers, G.M., Miller, R.L., Mattrazzo, A.M. (1999) Effectiveness of sanitizing agents in inactivating Escherichia coli in golden delicious apples, Journal of Food Science, 64 (4), 7347
Gronholm, L., Wirtanem, G., Ahlgren, K., Nordstrom, K., Sjoberg, A. (1999) Screening of antimicrobial activities of disinfectants and cleaning agents against foodborne spoilage microbes, Zeitschrift für Lebensmitteluntersuchung und -Forschung A, 208, 289-298.
Block, S.S. (2001) Disinfection, Sterilization and Preservation, Fifth Edition, Lippincott Williams & Wilkins, 135-146, 185-191.
Juven, B.J., Pierson, M.D. (1996) Antibacterial effects of hydrogen peroxide and methods for its detection and quantitation. Journal of Food Protection, 59 (11), 1233-1241