Nadir Görülen Bir Böbrek Tümörü: Müsinöz Tubuler ve İğsi Hücreli Karsinoma

Year 2018, Volume: 44 Issue: 3, 213 - 216, 01.12.2018

Mine Özşen , Berna Aytaç Vuruşkan , Hakan Vuruşkan

https://doi.org/10.32708/uutfd.465611

Abstract

Müsinöz tübüler ve iğsi
hücreli karsinoma; oldukça nadir görülen renal epitelyal bir neoplazmdır. Olgu
sunumumuzda müsinöz tübüler ve iğsi hücreli karsinoma saptanan olgu sunulmuş ve
hastalığın epidemiyolojisi, radyolojik bulguları ve histopatolojik özellikleri
ilgili literatür eşliğinde kısaca tartışılmıştır. 43 yaşındaki erkek hasta, sol
yan ağrısı şikayeti ile başvurduğu dış merkezde yapılan radyolojik incelemede,
sol böbreğinde kitle saptanması üzerine ileri tanı ve tedavi için hastanemiz
üroloji polikliniğine yönlendirildi. Yapılan fizik muayene ve tetkikler
doğrultusunda renal hücreli karsinoma düşünülen olguya radikal nefrektomi
operasyonu planlandı. Materyalden hazırlanan kesitlerin mikroskobik
incelemesinde; miksoid stroma içerisinde, eozinofilik sitoplazmalı, iğsi
şekilli, düşük gradeli nükleer özellikler gösteren hücrelerin, uzamış veya
birbiri ile anastomozlaşan tubul benzeri yapılanmalarından oluşan tümöral
lezyon dikkati çekti. Histopatolojik ve immünohistokimyasal bulgular
doğrultusunda olguya müsinöz tübüler ve iğsi hücreli karsinoma tanısı verildi.
Tüm renal neoplazilerin %1'den azını oluşturan bu tümörlerin prognozu, diğer
epitelyal böbrek tümörlerine kıyasla daha iyidir. Bu nedenle müsinöz tübüler ve
iğsi hücreli karsinoma olgularını ayırıcı tanıya girdikleri papiller renal
hücreli karsinoma olgularından ayırmak son derece önemlidir.

Keywords

Müsinöz tubuler ve iğsi hücreli karsinoma, Patoloji, Renal tümör

A Rarely Seen Renal Epithelial Tumor: Mucinous Tubular and Spindle Cell Carcinoma

Abstract

Mucinous tubular and spindle cell carcinoma has
recently been recognized as a rare distinctive type of renal epithelial
carcinoma. In our case report, we report a case of mucinous tubular and spindle
cell carcinoma and epidemiology, radiological findings and histopathologic
features of the disease were briefly discussed in literature data. A
43-year-old male was referred to our urology outpatient clinic for further
diagnosis and treatment after a mass on the left kidney was detected in a
radiological examination at the external center with the complaint of left
flank pain. Radical nephrectomy was planned for the case who was thought to
have a diagnosis of renal cell carcinoma according to physical examination and
tests. In the microscopic examination of the specimen, tumoral lesion
consisting of elongated or anastomotic tubulus-like structures of the spindle
shaped cells with eosinophilic cytoplasm indicating low-grade nuclear features
consistent in myxoid stroma were observed. The patient was diagnosed as
mucinous tubular and spindle cell carcinoma according to the histopathological
and immunohistochemical findings. These tumors, which constitute less than 1%
of all renal neoplasms, have a better prognosis than other epithelial renal
tumors. Therefore, it is very important to distinguish mucinous tubular and
spindle cell carcinoma cases from papillary renal cell carcinoma cases in
differential diagnosis.

Keywords

Mucinous tubular and Spindle cell carcinoma, Pathology, Renal tumor

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