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Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi

Year 2022, Volume: 48 Issue: 1, 91 - 97, 01.04.2022
https://doi.org/10.32708/uutfd.1074846

Abstract

Bu çalışmada, perkütan transtorasik akciğer biyopsi (PTAB) işlemi yapılan hastalarda pnömotoraks oranlarımızı ve pnömotoraks ile ilişkili risk faktörlerinin değerlendirilmesini amaçladık. Kliniğimizde yapılan 754 PTAB işlemine ait radyolojik görüntüler, raporları ve patoloji sonuçları retrospektif olarak incelendi. Pnömotoraks ve pulmoner hemoraji (PH) insidansı ve PH tipleri belirlendi. Biyopsi ilişkili pnömotoraks 143 hastada (%42,56) saptandı. Bu hastaların 130'unda (%90,91) ek tedavi gerekmezken, 13'ünde (%9,09) kateter drenajı uygulandı. Hastaların 153’ünde (%45,54) PH olup 124 hastada (%36,91) tip 1 (trakt hemorajisi), 29 hastada (%8,63) tip 2 (perilezyon hemorajisi) hemoraji mevcuttu. Amfizem varlığı, plevra-lezyon mesafesinin artması, plevra-cilt mesafesinin azalması, işlem sırasında iğne ile fissür geçilmesi, lezyonun perifissürel yerleşimli olması pnömotoraks riskini artıran faktörler olarak bulundu (sırasıyla p<0,001, p<0,001, p=0,007, p=0,017, p= 0,034). PH varlığı ve tipi ile pnömotoraks sıklığı arasında ilişki saptanmadı. Ancak trakt hemorajisinin, pnömotoraks gelişen hastalarda göğüs tüpü yerleştirilmesi için koruyucu faktör olduğu görüldü. PTAB akciğer kitlelerinin tanısında kabul edilebilir komplikasyon oranlarıyla güvenli ve etkili bir yöntemdir. PTAB’ye sekonder gelişen trakt hemorajisi, total pnömotoraks oranını azaltmasa da, kateterizasyon ihtiyacını minimize etmektedir.

References

  • 1. Callister ME, Baldwin DR, Akram AR, et al. British Thoracic Society Pulmonary Nodule Guideline Development Group; British Thoracic Society Standards of Care Committee. British Thoracic Society guidelines for the investigation and management of pulmonary nodules. Thorax 2015;70(2):1-54.
  • 2. Manhire A, Charig M, Clelland C, et al. Guidelines for radiologically guided lung biopsy Thorax 2003;58:920-36.
  • 3. Boskovic T, Stanic J, Pena-Karan S, et al. Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance. J Thorac Dis. 2014;6(1):99-107.
  • 4. Kim YS, Kim EY, Ahn HK, et al. Prognostic significance of CT-emphysema score in patients with advanced squamous cell lung cancer. J Thorac Dis 2016;8(8):1966-73.
  • 5. Tai R, Dunne RM, Trotman-Dickenson B, et al. Frequency and Severity of Pulmonary Hemorrhage in Patients Undergoing Percutaneous CT-guided Transthoracic Lung Biopsy: Single-Institution Experience of 1175 Cases. Radiology. 2016;279(1):287-96.
  • 6. Topal U, Berkman YM. Effect of needle tract bleeding on occurrence of pneumothorax after transthoracic needle biopsy. Eur J Radiol 2005;53(3):495-9.
  • 7. Sabatino V, Russo U, D'Amuri F, et al. Pneumothorax and pulmonary hemorrhage after CT-guided lung biopsy: incidence, clinical significance and correlation. Radiol Med 2021;126(1):170-7.
  • 8. De Filippo M, Saba L, Silva M, et al. CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage? Diagn Interv Radiol 2014;20(5):421-5.
  • 9. Khan MF, Straub R, Moghaddam SR, et al. Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy. Eur Radiol 2008;18(7):1356-63.
  • 10. Li Y, Du Y, Yang HF, Yu JH, Xu XX. CT-guided percutaneous core needle biopsy for small (≤20 mm) pulmonary lesions. Clin Radiol 2013;68(1):43-8.
  • 11. Lee HY, Lee IJ. Assessment of Independent Risk Factors of Developing Pneumothorax During Percutaneous Core Needle Lung Biopsy: Focus on Lesion Depth. Iran J Radiol 2016;13(4):e30929.
  • 12.Heerink WJ, de Bock GH, de Jonge GJ, Groen HJ, Vliegenthart R, Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: meta-analysis. Eur Radiol 2017;27(1):138-48.
  • 13.Yeow KM, See LC, Lui KW, et al. Risk factors forpneumothorax and bleeding after CT-guided percutaneous coaxial cutting needle biopsy of lung lesions. J Vasc IntervRadiol 2001;12(11):1305-12.
  • 14.Cox JE, Chiles C, McManus CM, Aquino SL, Choplin RH. Transthoracic needle aspiration biopsy: variables that affect risk of pneumothorax. Radiology. 1999;212(1):165-8.
  • 15.Heck SL, Blom P, Berstad A. Accuracy and complications in computed tomography fluoroscopy-guided needle biopsies of lung masses. Eur Radiol. 2006;16(6):1387-92.
  • 16.Huo YR, Chan MV, Habib AR, Lui I, Ridley L. Post-Biopsy Manoeuvres to Reduce Pneumothorax Incidence in CT-GuidedTransthoracic Lung Biopsies: A Systematic Review and Meta-analysis. Cardiovasc Intervent Radiol. 2019;42(8):1062-72.

Evaluation of Pneumothorax Risk Factors in Computed Tomography-Guided Transthoracic Fine Needle Aspiration Biopsies

Year 2022, Volume: 48 Issue: 1, 91 - 97, 01.04.2022
https://doi.org/10.32708/uutfd.1074846

Abstract

In this study, we aimed to evaluate our pneumothorax rates and risk factors associated with pneumothorax in patients who underwent percutaneous transthoracic lung biopsy (PTAB). Radiological images, reports, and pathology results of 754 PTAB procedures performed in our clinic were reviewed retrospectively. The incidence of pneumothorax and pulmonary hemorrhage (PH) and PH types were determined. Biopsy-associated pneumothorax was detected in 143 patients (42.56%). Additional treatment was not required in 130 (90.91%) of these patients, while catheter drainage was performed in 13 (9.09%) patients. PH occurred in 153 (45.54%) patients, 124 (36.91%) had type 1 (tract hemorrhage) and 29 (8.63%) had type 2 (perilesional hemorrhage) hemorrhage. The presence of emphysema, increased pleural lesion distance, decreased pleural skin distance, passing through fissure with a needle during the procedure, and perifissurel localization of the lesion were found to increase the risk of pneumothorax (p<0.001, p<0.001, p=0.007, p=0.017, p= 0.034, respectively). The presence and type of PH did not affect the frequency of pneumothorax. However, tract hemorrhage was a protective factor for chest tube insertion in patients who developed pneumothorax. PTAB is a safe and effective method with acceptable complication rates in the diagnosis of lung masses. Although tract hemorrhage secondary to PTAB does not reduce the overall pneumothorax rate, it minimizes chest tube insertion.

References

  • 1. Callister ME, Baldwin DR, Akram AR, et al. British Thoracic Society Pulmonary Nodule Guideline Development Group; British Thoracic Society Standards of Care Committee. British Thoracic Society guidelines for the investigation and management of pulmonary nodules. Thorax 2015;70(2):1-54.
  • 2. Manhire A, Charig M, Clelland C, et al. Guidelines for radiologically guided lung biopsy Thorax 2003;58:920-36.
  • 3. Boskovic T, Stanic J, Pena-Karan S, et al. Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance. J Thorac Dis. 2014;6(1):99-107.
  • 4. Kim YS, Kim EY, Ahn HK, et al. Prognostic significance of CT-emphysema score in patients with advanced squamous cell lung cancer. J Thorac Dis 2016;8(8):1966-73.
  • 5. Tai R, Dunne RM, Trotman-Dickenson B, et al. Frequency and Severity of Pulmonary Hemorrhage in Patients Undergoing Percutaneous CT-guided Transthoracic Lung Biopsy: Single-Institution Experience of 1175 Cases. Radiology. 2016;279(1):287-96.
  • 6. Topal U, Berkman YM. Effect of needle tract bleeding on occurrence of pneumothorax after transthoracic needle biopsy. Eur J Radiol 2005;53(3):495-9.
  • 7. Sabatino V, Russo U, D'Amuri F, et al. Pneumothorax and pulmonary hemorrhage after CT-guided lung biopsy: incidence, clinical significance and correlation. Radiol Med 2021;126(1):170-7.
  • 8. De Filippo M, Saba L, Silva M, et al. CT-guided biopsy of pulmonary nodules: is pulmonary hemorrhage a complication or an advantage? Diagn Interv Radiol 2014;20(5):421-5.
  • 9. Khan MF, Straub R, Moghaddam SR, et al. Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy. Eur Radiol 2008;18(7):1356-63.
  • 10. Li Y, Du Y, Yang HF, Yu JH, Xu XX. CT-guided percutaneous core needle biopsy for small (≤20 mm) pulmonary lesions. Clin Radiol 2013;68(1):43-8.
  • 11. Lee HY, Lee IJ. Assessment of Independent Risk Factors of Developing Pneumothorax During Percutaneous Core Needle Lung Biopsy: Focus on Lesion Depth. Iran J Radiol 2016;13(4):e30929.
  • 12.Heerink WJ, de Bock GH, de Jonge GJ, Groen HJ, Vliegenthart R, Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: meta-analysis. Eur Radiol 2017;27(1):138-48.
  • 13.Yeow KM, See LC, Lui KW, et al. Risk factors forpneumothorax and bleeding after CT-guided percutaneous coaxial cutting needle biopsy of lung lesions. J Vasc IntervRadiol 2001;12(11):1305-12.
  • 14.Cox JE, Chiles C, McManus CM, Aquino SL, Choplin RH. Transthoracic needle aspiration biopsy: variables that affect risk of pneumothorax. Radiology. 1999;212(1):165-8.
  • 15.Heck SL, Blom P, Berstad A. Accuracy and complications in computed tomography fluoroscopy-guided needle biopsies of lung masses. Eur Radiol. 2006;16(6):1387-92.
  • 16.Huo YR, Chan MV, Habib AR, Lui I, Ridley L. Post-Biopsy Manoeuvres to Reduce Pneumothorax Incidence in CT-GuidedTransthoracic Lung Biopsies: A Systematic Review and Meta-analysis. Cardiovasc Intervent Radiol. 2019;42(8):1062-72.
There are 16 citations in total.

Details

Primary Language Turkish
Subjects Radiology and Organ Imaging
Journal Section Research Article
Authors

Erdi Tangobay 0000-0003-1820-6413

Erdem Birgi 0000-0001-7808-7300

Önder Eraslan 0000-0001-8904-1412

Onur Ergun 0000-0002-0495-0500

Hasanali Durmaz 0000-0003-3230-9240

Azad Hekimoğlu 0000-0001-7853-019X

Tuğba Taşkın Türkmenoğlu 0000-0001-6314-2928

Baki Hekimoğlu 0000-0002-1824-5853

Publication Date April 1, 2022
Acceptance Date April 29, 2022
Published in Issue Year 2022 Volume: 48 Issue: 1

Cite

APA Tangobay, E., Birgi, E., Eraslan, Ö., Ergun, O., et al. (2022). Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 48(1), 91-97. https://doi.org/10.32708/uutfd.1074846
AMA Tangobay E, Birgi E, Eraslan Ö, Ergun O, Durmaz H, Hekimoğlu A, Taşkın Türkmenoğlu T, Hekimoğlu B. Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi. Uludağ Tıp Derg. April 2022;48(1):91-97. doi:10.32708/uutfd.1074846
Chicago Tangobay, Erdi, Erdem Birgi, Önder Eraslan, Onur Ergun, Hasanali Durmaz, Azad Hekimoğlu, Tuğba Taşkın Türkmenoğlu, and Baki Hekimoğlu. “Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 48, no. 1 (April 2022): 91-97. https://doi.org/10.32708/uutfd.1074846.
EndNote Tangobay E, Birgi E, Eraslan Ö, Ergun O, Durmaz H, Hekimoğlu A, Taşkın Türkmenoğlu T, Hekimoğlu B (April 1, 2022) Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 48 1 91–97.
IEEE E. Tangobay, E. Birgi, Ö. Eraslan, O. Ergun, H. Durmaz, A. Hekimoğlu, T. Taşkın Türkmenoğlu, and B. Hekimoğlu, “Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi”, Uludağ Tıp Derg, vol. 48, no. 1, pp. 91–97, 2022, doi: 10.32708/uutfd.1074846.
ISNAD Tangobay, Erdi et al. “Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi 48/1 (April 2022), 91-97. https://doi.org/10.32708/uutfd.1074846.
JAMA Tangobay E, Birgi E, Eraslan Ö, Ergun O, Durmaz H, Hekimoğlu A, Taşkın Türkmenoğlu T, Hekimoğlu B. Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi. Uludağ Tıp Derg. 2022;48:91–97.
MLA Tangobay, Erdi et al. “Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi”. Uludağ Üniversitesi Tıp Fakültesi Dergisi, vol. 48, no. 1, 2022, pp. 91-97, doi:10.32708/uutfd.1074846.
Vancouver Tangobay E, Birgi E, Eraslan Ö, Ergun O, Durmaz H, Hekimoğlu A, Taşkın Türkmenoğlu T, Hekimoğlu B. Bilgisayarlı Tomografi Eşliğinde Transtorasik İnce İğne Aspirasyon Biyopsilerinde Pnömotoraks Risk Faktörlerinin Değerlendirilmesi. Uludağ Tıp Derg. 2022;48(1):91-7.

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