Efficacy of intravenous phenylbutazone for pain management in dogs undergoing ovariohysterectomy

Year 2019, , 112 - 118, 30.12.2019

Murat Kibar

https://doi.org/10.31797/vetbio.599784

Abstract

The aim of the
present study was to evaluate the efficacy and analgesic duration of single
dose of PBZ administered the IV route immediately before induction of
anesthesia in dogs undergoing elective OVH. Eight-teeen sexually intact female
dogs (weiging between 4.5 and 28 kg, and 1 to 8 yrs of age) referred for OVH procedure from a local shelter at regular intervals over 4
months were included in the study. The dogs were administered PBZ on the basis
of their respective treatment group (20 mg/kg, IV administration) immediately
before anesthetic induction. For the IV treatment, PBZ was administered over a
period of one minute. Time of completion of PBZ administration was designed as
time 0. In control group, 0.9% NaCl was administered IV as over a period of one
minute. Throughout the study, pre and postoperative pain was assessed at
baseline (before induction of anesthesia) and then at 0.5, 1, 2, 3, 8, and 24
hrs after the surgery. Group IV had significantly lower CMPS-SF scores than the control group at
the 0.5, 1, 2, 3, and 8 hour postoperative periods. In conclusion, a single
dose of PBZ administered via the IV route before surgery may be particularly
beneficial for acheiving reasonable perioperative analgesia, but not in
postoperative period. 

Keywords

Ovariyohisterektomi, Ağrı, Fenilbutazon

Supporting Institution

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Project Number

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Thanks

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