The effect of main pulmonary artery diameter on the prognosis of COVID-19 patients in the ICU

Year 2022, Volume: 5 Issue: 3, 778 - 781, 30.05.2022

Gökhan Çoraplı , Ercan Çil , Ayşe Şahin Tutak , Mahmut Çoraplı

https://doi.org/10.32322/jhsm.1072443

Abstract

Aim: The aim of this study was to examine the effect of main pulmonary artery diameter (MPAD), which is evaluated in patients when first admitted to the intensive care unit due to COVID-19, on mortality.
Material and Method: Thoracic computed tomography examinations performed during the initial admission to hospital of patients who were treated in the intensive care unit between October 1, 2020, and June 1, 2021, were evaluated retrospectively. Cox regression analysis was performed with the program R-Project to evaluate the relationship between MPAD and mortality.
Results: No significant correlation was found between MPAD and mortality in models used with or without adjusting for age and sex (respectively P: 0.890 and P: 0.920).
Conclusion: The MPAD value measured at the initial admission of COVID-19 patients hospitalized in the intensive care unit is not a parameter that can be used to predict mortality.

Keywords

COVID-19, main pulmonary artery diameter, intensive care unit, mortality

References

• Çil B, Kabak M. Comparative evaluation of tocilizumab versus high dose methylprednisolonetherapy in mild acute respiratory distress syndrome related to COVID-19 pneumonia: a retrospective cohort study. New Trend Med Sci 2021; 2: 130-5.
• Hui DS, Azhar EI, Madani TA, et al. The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health—The latest 2019 novel coronavirus outbreak in Wuhan, China. Int J Infect Dis 2020; 91: 264-6.
• Sohrabi C, Alsafi Z, O'neill N, et al. World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19). Int J Surg 2020; 76: 71-6.
• Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109: 102433.
• Sharma A, Tiwari S, Deb MK, Marty JL. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies. Int J Antimicrob Agents 2020; 56: 106054.
• Libby P, Lüscher T. COVID-19 is, in the end, an endothelial disease. Eur Heart J 2020; 41: 3038-44.
• Hoeper MM, Bogaard HJ, Condliffe R, et al. Definitions and diagnosis of pulmonary hypertension. Turk Kardiyoloji Dernegi Arsivi 2014; 42: 55-66.
• Douschan P, Kovacs G, Avian A, et al. Mild elevation of pulmonary arterial pressure as a predictor of mortality. Am J Respir Crit Care Med 2018; 197: 509-16.
• Simonneau G, Galie N, Rubin LJ, et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol 2004; 43: 5-12.
• Nazzareno G, Marc H, Jean LV, Simon G, Irene L, Adam T. ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Eur Heart J 2016; 37: 67-119.
• Tan RT, Kuzo R, Goodman LR, Siegel R, Haasler GR, Presberg KW. Utility of CT scan evaluation for predicting pulmonary hypertension in patients with parenchymal lung disease. Chest 1998; 113: 1250-6.
• Republic of Turkey Ministry of Healhty, Adult patient treatment in COVID-19, December 2021.https://covid19.saglik.gov.tr/Eklenti/42169/0/covid19rehberieriskinhastayonetimivetedavi20122021v6pdf.pdf. (Accessed February 10,2022).
• Truong QA, Massaro JM, Rogers IS, et al. Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomographyclinical perspective: The Framingham Heart Study. Circ Cardiovasc Imaging 2012; 5: 147-54.
• Mahammedi A, Oshmyansky A, Hassoun PM, Thiemann DR, Siegelman SS. Pulmonary artery measurements in pulmonary hypertension: the role of computed tomography. J Thorac Imaging 2013; 28: 96-103.
• R Core Team (2020). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. URL https://www.R-project.org/.
• Zhu QQ, Gong T, Huang GQ, et al. Pulmonary artery trunk enlargement on admission as a predictor of mortality in in-hospital patients with COVID-19. Jpn J Radiol 2021; 1-9.
• Erdoğan M, Öztürk S, Erdöl MA, et al. Prognostic utility of pulmonary artery and ascending aorta diameters derived from computed tomography in COVID‐19 patients. Echocardiography 2021; 38: 1543-51.
• Yildiz M, Yadigar S, Yildiz BŞ, et al. Evaluation of the relationship between COVID-19 pneumonia severity and pulmonary artery diameter measurement. Herz 2021; 46: 56-62.
• Esposito A, Palmisano A, Toselli M, et al. Chest CT-derived pulmonary artery enlargement at the admission predicts overall survival in COVID-19 patients: insight from 1461 consecutive patients in Italy. Eur Radiol 2021; 31: 4031-41.