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Vücut Geliştiricide İntramuskuler Synthol Enjeksiyonuna Bağlı Lipoid Pnömoni

Yıl 2019, Cilt: 6 Sayı: 1, 48 - 51, 20.03.2019

Nesrin Öcal , Armağan Günal Yakup Arslan Berat Kaçmaz Ali Coşkun Bahadır Can Karan Deniz Doğan , Cantürk Taşçı Ergün Uçar

Öz

Bu makalede kas dolgusu amacıyla sentetik bir
yağ türevi olan “Synthol” un tekrarlayan intramuskuler kullanımı nedeniyle
gelişen kronik eksojen lipoid pnömoni olgusu sunulmuştur. Göğüs kaslarını
büyütmek için Synthol kullanan 40 yaşında erkek hasta, bir yıl içinde ilerleyen
nefes darlığı ile birlikte polikliniğimize başvurdu. Toraks tomografisinde
interstisyel akciğer hastalığı ile uyumlu retikülasyonlar ve septal
kalınlaşmalar izlenmekteydi. Hastaya bronkoskopi yapıldı. Bronkoalveolar lavaj ve
transbronşiyal biyopsi (TBB) alındı. TBB'nin histopatolojik incelemesinde,
intraalveoler ve interstisyel yağlı makrofajlar, yağ partikülleri etrafındaki
dev hücreler ve ekstraselüler yağ partikülleri gözlendi. Örnek “lipoid pnömoni”
olarak raporlandı. Bizim bilgimize göre Synthol'un intramusküler kullanımına
bağlı ekzojen lipoid pnömonisi şimdiye kadar bildirilmemiştir ve olgumuz
literatürdeki ilk olgudur.

Anahtar Kelimeler

Synthol Lipoid Pnömoni Sentetik Yağ Vücut Geliştirme

Kaynakça

  • 1. Gondouin A, Manzoni PH, Ranfaing E, et al. Exogenous lipid pneumonia: a retrospective multicentric study of 44 cases in France. Eur Respir J. 1996;9:1463–9.
  • 2. Cherrez Ojeda I, Calderon JC, Guevara J, Cabrera D, Calero E, Cherrez A. Exogenous lipid pneumonia related to long-term use of Vicks VapoRub by an adult patient: a case report. BMC Ear, Nose Throat Disord. 2016;16:11.
  • 3. Betancourt SL, Martinez-Jimenez S, Rossi SE, Truong MT, Carrillo J, Erasmus JJ.Lipoid pneumonia:spectrum of clinical and radiologic manifestations. Am J Roentgenol. 2010;194:103-9.
  • 4. Laughlin GF. Studies of pneumonia following injections of oil. Am J Pathol. 1925;1:407–14.
  • 5. Marchiori E, Zanetti G, Mano CM, Irion KL, Daltro PA, Hochhegger B. Lipoid pneumonia in 53 patients after aspiration of mineral oil: comparison of high-resolution computed tomography findings in adults and children. J Comput Assist Tomogr. 2010; 34(1): 9-12.
  • 6. Rahaghi F, Varasteh A, Memarpour R, Tashtoush B. Teppanyaki/Hibachi Pneumonitis: An Exotic Cause of Exogenous Lipoid Pneumonia. Case Rep Pulmonol. 2016; 2016: 1035601.
  • 7. Hotta T, Tsubata Y, Okimoto T, Hoshino T, Hamaguchi S, Isobe T. Exogenous lipoid pneumonia caused by herbicide inhalation. Respirol Case Rep. 2016;4(5): e00172.
  • 8. Yasui H, Yokomura K, Suda T. A severe case of acute exogenous lipoid pneumonia treated with systemic corticosteroid. Respir Med Case Rep. 2016;17: 64–7.
  • 9. Russell M, Storck A, Ainslie M. Acute respiratory distress following intravenous injection of an oil-steroid solution. Can Respir J. 2011;18(4): 59–61.
  • 10. Fumo G, Ferreli C, Murgia S, Galletti R, Pau M. A serious complication due to liquid silicone injection in the legs for cosmetic purpose. Clin Ter. 2013;164(5):377-9.
  • 11. Gersuny R. Ueber eine subcutyane Prothese. Z Heilk. 1900;30:1–5.
  • 12. Pupka A, Sikora J, Mauricz J, Cios D, Plonek T. The usage of synthol in the body building. Polim Med. 2009;39:63–5.
  • 13. Ghandourah S, Hofer MJ, Kießling A, El-Zayat B, Schofer MD. Painful muscle fibrosis following synthol injections in a bodybuilder: a case report. J Med Case Rep. 2012;6:248.
  • 14. https://www.pneumotox.com/drug/view/1171/synthol

Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder

Yıl 2019, Cilt: 6 Sayı: 1, 48 - 51, 20.03.2019

Nesrin Öcal , Armağan Günal Yakup Arslan Berat Kaçmaz Ali Coşkun Bahadır Can Karan Deniz Doğan , Cantürk Taşçı Ergün Uçar

Öz

We report a case of chronic exogenous lipoid
pneumonia that developed due to recurrent intramuscular use of “Synthol”, a
synthetic oil derivative, for muscle filling. 40-year-old man, who had used
Synthol to enlarge his pectoral muscles, was admitted to the chest diseases
polyclinic with shortness of breath progressing within a year. On computerized
tomography of thorax there were reticulations and septal thickenings consistent
with interstitial lung disease. The patient underwent bronchoscopy.
Bronchoalveolar lavage and transbronchial biopsy (TBB) were performed. In the
histopathologic study of TBB, intraalveolar and interstitial fatty macrophages,
giant cells around fat particles and extracellular fat particles were observed
and the specimen was reported as "lipoid pneumonia". According to our
knowledge, exogenous lipoid pneumonia due to intramuscular use of Synthol has
not been reported heretofore and this is the first case in the literature.

Anahtar Kelimeler

Bodybuilder Lipoid Pneumonia Synthetic Oil Synthol

Kaynakça

  • 1. Gondouin A, Manzoni PH, Ranfaing E, et al. Exogenous lipid pneumonia: a retrospective multicentric study of 44 cases in France. Eur Respir J. 1996;9:1463–9.
  • 2. Cherrez Ojeda I, Calderon JC, Guevara J, Cabrera D, Calero E, Cherrez A. Exogenous lipid pneumonia related to long-term use of Vicks VapoRub by an adult patient: a case report. BMC Ear, Nose Throat Disord. 2016;16:11.
  • 3. Betancourt SL, Martinez-Jimenez S, Rossi SE, Truong MT, Carrillo J, Erasmus JJ.Lipoid pneumonia:spectrum of clinical and radiologic manifestations. Am J Roentgenol. 2010;194:103-9.
  • 4. Laughlin GF. Studies of pneumonia following injections of oil. Am J Pathol. 1925;1:407–14.
  • 5. Marchiori E, Zanetti G, Mano CM, Irion KL, Daltro PA, Hochhegger B. Lipoid pneumonia in 53 patients after aspiration of mineral oil: comparison of high-resolution computed tomography findings in adults and children. J Comput Assist Tomogr. 2010; 34(1): 9-12.
  • 6. Rahaghi F, Varasteh A, Memarpour R, Tashtoush B. Teppanyaki/Hibachi Pneumonitis: An Exotic Cause of Exogenous Lipoid Pneumonia. Case Rep Pulmonol. 2016; 2016: 1035601.
  • 7. Hotta T, Tsubata Y, Okimoto T, Hoshino T, Hamaguchi S, Isobe T. Exogenous lipoid pneumonia caused by herbicide inhalation. Respirol Case Rep. 2016;4(5): e00172.
  • 8. Yasui H, Yokomura K, Suda T. A severe case of acute exogenous lipoid pneumonia treated with systemic corticosteroid. Respir Med Case Rep. 2016;17: 64–7.
  • 9. Russell M, Storck A, Ainslie M. Acute respiratory distress following intravenous injection of an oil-steroid solution. Can Respir J. 2011;18(4): 59–61.
  • 10. Fumo G, Ferreli C, Murgia S, Galletti R, Pau M. A serious complication due to liquid silicone injection in the legs for cosmetic purpose. Clin Ter. 2013;164(5):377-9.
  • 11. Gersuny R. Ueber eine subcutyane Prothese. Z Heilk. 1900;30:1–5.
  • 12. Pupka A, Sikora J, Mauricz J, Cios D, Plonek T. The usage of synthol in the body building. Polim Med. 2009;39:63–5.
  • 13. Ghandourah S, Hofer MJ, Kießling A, El-Zayat B, Schofer MD. Painful muscle fibrosis following synthol injections in a bodybuilder: a case report. J Med Case Rep. 2012;6:248.
  • 14. https://www.pneumotox.com/drug/view/1171/synthol
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular İç Hastalıkları
Bölüm Olgu Sunumu
Yazarlar

Nesrin Öcal 0000-0002-3789-7769

Armağan Günal Bu kişi benim 0000-0002-9923-926X

Yakup Arslan Bu kişi benim 0000-0002-9079-1701

Berat Kaçmaz Bu kişi benim 0000-0001-8104-6921

Ali Coşkun Bu kişi benim 0000-0003-2286-0135

Bahadır Can Karan Bu kişi benim 0000-0003-1559-6516

Deniz Doğan 0000-0003-2596-3113

Cantürk Taşçı Bu kişi benim 0000-0002-8789-7775

Ergün Uçar Bu kişi benim

Yayımlanma Tarihi 20 Mart 2019
Gönderilme Tarihi 31 Ağustos 2018
Yayımlandığı Sayı Yıl 2019 Cilt: 6 Sayı: 1

Kaynak Göster

APA Öcal, N., Günal, A., Arslan, Y., Kaçmaz, B., vd. (2019). Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 6(1), 48-51.
AMA Öcal N, Günal A, Arslan Y, Kaçmaz B, Coşkun A, Karan BC, Doğan D, Taşçı C, Uçar E. Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder. MMJ. Mart 2019;6(1):48-51.
Chicago Öcal, Nesrin, Armağan Günal, Yakup Arslan, Berat Kaçmaz, Ali Coşkun, Bahadır Can Karan, Deniz Doğan, Cantürk Taşçı, ve Ergün Uçar. “Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 6, sy. 1 (Mart 2019): 48-51.
EndNote Öcal N, Günal A, Arslan Y, Kaçmaz B, Coşkun A, Karan BC, Doğan D, Taşçı C, Uçar E (01 Mart 2019) Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 6 1 48–51.
IEEE N. Öcal, A. Günal, Y. Arslan, B. Kaçmaz, A. Coşkun, B. C. Karan, D. Doğan, C. Taşçı, ve E. Uçar, “Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder”, MMJ, c. 6, sy. 1, ss. 48–51, 2019.
ISNAD Öcal, Nesrin vd. “Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 6/1 (Mart 2019), 48-51.
JAMA Öcal N, Günal A, Arslan Y, Kaçmaz B, Coşkun A, Karan BC, Doğan D, Taşçı C, Uçar E. Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder. MMJ. 2019;6:48–51.
MLA Öcal, Nesrin vd. “Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, c. 6, sy. 1, 2019, ss. 48-51.
Vancouver Öcal N, Günal A, Arslan Y, Kaçmaz B, Coşkun A, Karan BC, Doğan D, Taşçı C, Uçar E. Exogenous Lipoid Pneumonia Due To Intramuscular Injection of Synthol in a Bodybuilder. MMJ. 2019;6(1):48-51.
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